一名患单核细胞增多症的青春期前女性出现坏死性生殖器溃疡。
Necrotizing genital ulcerations in a premenarcheal female with mononucleosis.
作者信息
Hudson L B, Perlman S E
机构信息
Department of Obstetrics and Gynecology, United States Air Force Academy, Colorado Springs, Colorado, USA.
出版信息
Obstet Gynecol. 1998 Oct;92(4 Pt 2):642-4. doi: 10.1016/s0029-7844(98)00027-1.
BACKGROUND
Two cases of genital ulcerations caused by Epstein-Barr virus have been reported previously, one in a sexually active 23-year-old and another in a 14-year-old practicing cunnilingus.
CASE
We report a case of Epstein-Barr virus genital ulcerations in a premenarcheal virgin. Her systemic symptoms were atypical for mononucleosis. Necrotizing genital ulcerations preceded pharyngitis and oral lesions. Cervical adenopathy, fever, and splenomegaly never developed despite serologic evidence of acute mononucleosis.
CONCLUSION
Genital ulcerations can be the initial manifestation of Epstein-Barr virus in adolescents who are neither sexually active nor immunocompromised.
背景
先前已有两例由爱泼斯坦-巴尔病毒引起的生殖器溃疡病例报告，一例发生在一名有性活动的23岁患者身上，另一例发生在一名14岁口交的患者身上。
病例
我们报告一例青春期前处女发生爱泼斯坦-巴尔病毒生殖器溃疡的病例。她的全身症状不符合单核细胞增多症的典型表现。坏死性生殖器溃疡先于咽炎和口腔病变出现。尽管有急性单核细胞增多症的血清学证据，但从未出现颈部淋巴结病、发热和脾肿大。
结论
生殖器溃疡可能是爱泼斯坦-巴尔病毒在既无性活动又无免疫功能低下的青少年中的初始表现。
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