革兰氏阴性菌会产生能够杀死其他细菌的膜泡。
Gram-negative bacteria produce membrane vesicles which are capable of killing other bacteria.
作者信息
Li Z, Clarke A J, Beveridge T J
机构信息
Canadian Bacterial Disease Network, Department of Microbiology, College of Biological Science, University of Guelph, Guelph, Ontario, Canada N1G 2W1.
出版信息
J Bacteriol. 1998 Oct;180(20):5478-83. doi: 10.1128/JB.180.20.5478-5483.1998.
Abstract
Naturally produced membrane vesicles (MVs), isolated from 15 strains of gram-negative bacteria (Citrobacter, Enterobacter, Escherichia, Klebsiella, Morganella, Proteus, Salmonella, and Shigella strains), lysed many gram-positive (including Mycobacterium) and gram-negative cultures. Peptidoglycan zymograms suggested that MVs contained peptidoglycan hydrolases, and electron microscopy revealed that the murein sacculi were digested, confirming a previous modus operandi (J. L. Kadurugamuwa and T. J. Beveridge, J. Bacteriol. 174:2767-2774, 1996). MV-sensitive bacteria possessed A1alpha, A4alpha, A1gamma, A2alpha, and A4gamma peptidoglycan chemotypes, whereas A3alpha, A3beta, A3gamma, A4beta, B1alpha, and B1beta chemotypes were not affected. Pseudomonas aeruginosa PAO1 vesicles possessed the most lytic activity.
摘要
从15株革兰氏阴性菌（柠檬酸杆菌属、肠杆菌属、大肠杆菌属、克雷伯菌属、摩根氏菌属、变形杆菌属、沙门氏菌属和志贺氏菌属菌株）中分离出的天然产生的膜泡（MVs），能裂解许多革兰氏阳性菌（包括分枝杆菌）和革兰氏阴性菌培养物。肽聚糖酶谱分析表明MVs含有肽聚糖水解酶，电子显微镜显示胞壁质囊被消化，证实了先前的作用方式（J. L. 卡杜鲁加穆瓦和T. J. 贝弗里奇，《细菌学杂志》174:2767 - 2774，1996）。对MVs敏感的细菌具有A1α、A4α、A1γ、A2α和A4γ肽聚糖化学型，而A3α、A3β、A3γ、A4β、B1α和B1β化学型不受影响。铜绿假单胞菌PAO1膜泡具有最强的裂解活性。
相似文献
1
Gram-negative bacteria produce membrane vesicles which are capable of killing other bacteria.革兰氏阴性菌会产生能够杀死其他细菌的膜泡。
J Bacteriol. 1998 Oct;180(20):5478-83. doi: 10.1128/JB.180.20.5478-5483.1998.
2
Bacteriolytic effect of membrane vesicles from Pseudomonas aeruginosa on other bacteria including pathogens: conceptually new antibiotics.铜绿假单胞菌膜泡对包括病原体在内的其他细菌的溶菌作用：概念上的新型抗生素
J Bacteriol. 1996 May;178(10):2767-74. doi: 10.1128/jb.178.10.2767-2774.1996.
3
Bactericidal effect of gentamicin-induced membrane vesicles derived from Pseudomonas aeruginosa PAO1 on gram-positive bacteria.源自铜绿假单胞菌PAO1的庆大霉素诱导膜泡对革兰氏阳性菌的杀菌作用。
Can J Microbiol. 2002 Sep;48(9):810-20. doi: 10.1139/w02-077.
4
S-layered Aneurinibacillus and Bacillus spp. are susceptible to the lytic action of Pseudomonas aeruginosa membrane vesicles.具有S层的食酸戴尔福特菌和芽孢杆菌属对铜绿假单胞菌膜泡的裂解作用敏感。
J Bacteriol. 1998 May;180(9):2306-11. doi: 10.1128/JB.180.9.2306-2311.1998.
5
O-Acetylated peptidoglycan: controlling the activity of bacterial autolysins and lytic enzymes of innate immune systems.O-乙酰化肽聚糖：控制细菌自溶酶和先天免疫系统溶酶活性。
Int J Biochem Cell Biol. 2011 Dec;43(12):1655-9. doi: 10.1016/j.biocel.2011.08.007. Epub 2011 Aug 24.
6
The "hole" story of predatory outer-membrane vesicles.掠夺性外膜囊泡的“孔洞”故事
Can J Microbiol. 2018 Sep;64(9):589-599. doi: 10.1139/cjm-2017-0466.
7
Analysis of the sodium dodecyl sulfate-stable peptidoglycan autolysins of select gram-negative pathogens by using renaturing polyacrylamide gel electrophoresis.利用复性聚丙烯酰胺凝胶电泳分析特定革兰氏阴性病原体的十二烷基硫酸钠稳定的肽聚糖自溶素。
J Bacteriol. 1994 Sep;176(17):5225-32. doi: 10.1128/jb.176.17.5225-5232.1994.
8
The role of peptidoglycan hydrolases in the formation and toxicity of membrane vesicles.肽聚糖水解酶在膜泡形成及毒性中的作用
Microlife. 2022 Jun 30;3:uqac009. doi: 10.1093/femsml/uqac009. eCollection 2022.
9
Detection, cellular localization and antibacterial activity of two lytic enzymes of Pediococcus acidilactici ATCC 8042.检测、细胞定位和两株嗜酸乳杆菌 ATCC8042 溶菌酶的抗菌活性。
J Appl Microbiol. 2011 Sep;111(3):607-15. doi: 10.1111/j.1365-2672.2011.05088.x. Epub 2011 Jul 20.
10
A major autolysin of Pseudomonas aeruginosa: subcellular distribution, potential role in cell growth and division and secretion in surface membrane vesicles.铜绿假单胞菌的一种主要自溶素：亚细胞分布、在细胞生长与分裂中的潜在作用以及在表面膜泡中的分泌
J Bacteriol. 1996 May;178(9):2479-88. doi: 10.1128/jb.178.9.2479-2488.1996.
引用本文的文献
1
Enhanced Outer Membrane Vesicle Production in : From Metabolic Network Model to Designed Strain Lipidomic Profile.中增强外膜囊泡的产生：从代谢网络模型到设计菌株的脂质组学图谱
Int J Mol Sci. 2025 Jul 13;26(14):6714. doi: 10.3390/ijms26146714.
2
Bacterial extracellular vesicles target different bacterial species, impairing cell division and diminishing their pathogenicity.细菌细胞外囊泡靶向不同细菌物种，损害细胞分裂并降低其致病性。
Proc Natl Acad Sci U S A. 2025 May 6;122(18):e2416652122. doi: 10.1073/pnas.2416652122. Epub 2025 Apr 29.
3
Bacterial Extracellular Vesicles and Antimicrobial Peptides: A Synergistic Approach to Overcome Antimicrobial Resistance.细菌细胞外囊泡与抗菌肽：克服抗菌耐药性的协同方法
Antibiotics (Basel). 2025 Apr 19;14(4):414. doi: 10.3390/antibiotics14040414.
4
Extracellular Vesicle-Driven Crosstalk between Legume Plants and Rhizobia: The Peribacteroid Space of Symbiosomes as a Protein Trafficking Interface.豆科植物与根瘤菌之间细胞外囊泡驱动的串扰：共生体周细菌空间作为蛋白质运输界面
J Proteome Res. 2025 Jan 3;24(1):94-110. doi: 10.1021/acs.jproteome.4c00444. Epub 2024 Dec 12.
5
Impact of probiotics-derived extracellular vesicles on livestock gut barrier function.益生菌衍生的细胞外囊泡对家畜肠道屏障功能的影响。
J Anim Sci Biotechnol. 2024 Nov 7;15(1):149. doi: 10.1186/s40104-024-01102-8.
6
Outer Membrane Vesicles Formed by Clinical Strains May Be Incorporated into the Outer Membrane of Other Cells and Demonstrate Lytic Properties.临床分离株形成的外膜囊泡可能被整合到其他细胞的外膜中，并表现出溶细胞特性。
Molecules. 2024 Oct 12;29(20):4836. doi: 10.3390/molecules29204836.
7
Bacterial extracellular vesicles at the interface of gut microbiota and immunity.肠道微生物群和免疫的细菌细胞外囊泡。
Gut Microbes. 2024 Jan-Dec;16(1):2396494. doi: 10.1080/19490976.2024.2396494. Epub 2024 Sep 28.
8
Novel Nano Drug-Loaded Hydrogel Coatings for the Prevention and Treatment of CAUTI.用于预防和治疗导尿管相关尿路感染的新型载纳米药物水凝胶涂层
Adv Healthc Mater. 2024 Dec;13(30):e2401745. doi: 10.1002/adhm.202401745. Epub 2024 Aug 23.
9
Engineering Versatile Bacteria-Derived Outer Membrane Vesicles: An Adaptable Platform for Advancing Cancer Immunotherapy.工程化多功能细菌外膜囊泡：推进癌症免疫治疗的适应性平台。
Adv Sci (Weinh). 2024 Sep;11(33):e2400049. doi: 10.1002/advs.202400049. Epub 2024 Jul 1.
10
Insights into Bacterial Extracellular Vesicle Biogenesis, Functions, and Implications in Plant-Microbe Interactions.细菌细胞外囊泡的生物发生、功能及其在植物-微生物相互作用中的意义
Microorganisms. 2024 Mar 6;12(3):532. doi: 10.3390/microorganisms12030532.
本文引用的文献
1
Membrane-bound lytic endotransglycosylase in Escherichia coli.大肠杆菌中的膜结合溶菌内转糖基酶。
J Bacteriol. 1998 Jul;180(13):3441-7. doi: 10.1128/JB.180.13.3441-3447.1998.
2
S-layered Aneurinibacillus and Bacillus spp. are susceptible to the lytic action of Pseudomonas aeruginosa membrane vesicles.具有S层的食酸戴尔福特菌和芽孢杆菌属对铜绿假单胞菌膜泡的裂解作用敏感。
J Bacteriol. 1998 May;180(9):2306-11. doi: 10.1128/JB.180.9.2306-2311.1998.
3
Natural release of virulence factors in membrane vesicles by Pseudomonas aeruginosa and the effect of aminoglycoside antibiotics on their release.铜绿假单胞菌膜泡中致病因子的自然释放及氨基糖苷类抗生素对其释放的影响。
J Antimicrob Chemother. 1997 Nov;40(5):615-21. doi: 10.1093/jac/40.5.615.
4
Interactions between biofilms and the environment.生物膜与环境之间的相互作用。
FEMS Microbiol Rev. 1997 Jul;20(3-4):291-303. doi: 10.1111/j.1574-6976.1997.tb00315.x.
5
Bacteriolytic effect of membrane vesicles from Pseudomonas aeruginosa on other bacteria including pathogens: conceptually new antibiotics.铜绿假单胞菌膜泡对包括病原体在内的其他细菌的溶菌作用：概念上的新型抗生素
J Bacteriol. 1996 May;178(10):2767-74. doi: 10.1128/jb.178.10.2767-2774.1996.
6
A major autolysin of Pseudomonas aeruginosa: subcellular distribution, potential role in cell growth and division and secretion in surface membrane vesicles.铜绿假单胞菌的一种主要自溶素：亚细胞分布、在细胞生长与分裂中的潜在作用以及在表面膜泡中的分泌
J Bacteriol. 1996 May;178(9):2479-88. doi: 10.1128/jb.178.9.2479-2488.1996.
7
The release of outer membrane vesicles from the strains of enterotoxigenic Escherichia coli.产肠毒素大肠杆菌菌株外膜囊泡的释放
Microbiol Immunol. 1995;39(7):451-6. doi: 10.1111/j.1348-0421.1995.tb02228.x.
8
Release of the outer membrane vesicles from Vibrio cholerae and Vibrio parahaemolyticus.霍乱弧菌和副溶血性弧菌外膜囊泡的释放。
Microbiol Immunol. 1993;37(2):149-52. doi: 10.1111/j.1348-0421.1993.tb03192.x.
9
Specific and nonspecific responses of murine B cells to membrane blebs of Borrelia burgdorferi.小鼠B细胞对伯氏疏螺旋体膜泡的特异性和非特异性反应。
Infect Immun. 1993 Apr;61(4):1460-7. doi: 10.1128/iai.61.4.1460-1467.1993.
10
Preservation of surface lipids and determination of ultrastructure of Mycobacterium kansasii by freeze-substitution.通过冷冻置换法保存堪萨斯分枝杆菌的表面脂质并测定其超微结构。
Infect Immun. 1994 May;62(5):1542-50. doi: 10.1128/iai.62.5.1542-1550.1994.
Zotero 插件