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[鼻硬结病。病例报告]

[Rhinoscleroma. A case report].

作者信息

Valor García C, Castillo Serrano E, Martín del Guayo G, Bhathal Guede B, García Fernández E, Olalla Tabar A, Poch Broto J

机构信息

Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid, 28040, España.

出版信息

Acta Otorrinolaringol Esp. 1999 May;50(4):321-3.

Abstract

Rhinoscleroma is a chronic, specific, inflammatory granulomatous condition of the nose and other structures of the upper respiratory tract. It is caused by the bacterium Klebsiella rhinoscleromatis. We report a case in a 29-year-old black male emigrant who consulted for a 2-year history of hoarseness, cough, and nasal discharge. The diagnosis was scleroma with nasal, laryngeal, tracheal, and bronchial involvement and ulcerating and necrotizing lesions that caused respiratory obstruction. Bacterial over-infection responded to treatment with third-generation cephalosporins and clindamycin. The sclerotic lesions responded well to treatment with ciprofloxacin. We review the clinical findings at different stages, diagnostic options, and several treatments.

摘要

鼻硬结病是一种发生于鼻子及上呼吸道其他结构的慢性、特异性、炎症性肉芽肿疾病。它由鼻硬结克雷伯菌引起。我们报告一例29岁的黑人男性移民病例,该患者因声音嘶哑、咳嗽和流涕2年前来就诊。诊断为硬结病,累及鼻、喉、气管和支气管,伴有溃疡和坏死性病变,导致呼吸道梗阻。细菌重叠感染经第三代头孢菌素和克林霉素治疗有效。硬化性病变经环丙沙星治疗效果良好。我们回顾了不同阶段的临床发现、诊断方法及多种治疗手段。

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