Valdivia A, Alvarez M, Marrero M, Valdés O, Muné M
Instituto de Medicina Tropical Pedro Kouri.
Rev Cubana Med Trop. 1992;44(3):212-5.
The technique for the detection of fluorescent early antigen was compared to the classical method of viral isolation in cells from the human lung. The study was performed with the use of 85 urine samples from 64 patients presenting with HIV infection. The technique for the detection of fluorescent early antigens showed a sensitivity of 91%, an specificity of 97%, and a coincidence of 94% with respect to viral isolation. The main advantage of the technique for the detection of fluorescent early antigens with respect to viral isolation is that the former provides a quicker diagnosis of cytomegalovirus infection within 48-72 hours, besides being easy to perform.
将检测荧光早期抗原的技术与从人肺细胞中分离病毒的经典方法进行了比较。该研究使用了来自64例HIV感染患者的85份尿液样本。检测荧光早期抗原的技术显示出91%的灵敏度、97%的特异性以及与病毒分离法94%的符合率。检测荧光早期抗原的技术相对于病毒分离法的主要优势在于，除操作简便外，前者能在48至72小时内更快地诊断巨细胞病毒感染。
