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匈牙利成年住院急性肝炎患者临床、实验室及血清学检查结果的随访与康复特征

Follow up of clinical, laboratory, and serological findings of adult Hungarian hospitalized acute hepatitis patients and characteristics of recovery.

作者信息

Kassas A L

机构信息

3rd Department of Internal Medicine, Szent László Hospital, Budapest, Hungary.

出版信息

Acta Microbiol Immunol Hung. 1998;45(2):209-19.

PMID:9768289
Abstract

Follow-up features of acute viral hepatitis were evaluated of 210 hospitalized adult patients. HA, HB, HC, and NON A-C H were diagnosed in 68 patients, 84 patients, 22 patients, and 36 patients, respectively. Post-hepatitis syndrome was shown in about 20.6%, 19%, 45.5%, and 25% of patients with HA, HB, HC, and NON A-C H, respectively. At three months, the recovery was shown in about 61.7%, 69%, 13.6%, and 63.9% of patients with HA, HB, HC, and NON A-C H, respectively. Factors of sex, age, and severity of acute phase had no effect on the protracted rate in all types, except in HB. After six months, the disease remained active in 1.5%, 6%, 69%, 8.3% of patients with HA, HB, HC, NON A-C H, respectively. Factors of sex, age, severity of acute phase had no effect on the chronicity rate in different types, except HB. It was more significantly more frequent in males, elderly persons, and mild acute phase in chronic HB cases. Diabetes mellitus was also significantly more frequent in chronic HB cases. Flat pattern of ALT elevation was significantly more frequent in chronic HB and NON A-C H cases.

摘要

对210例住院成年急性病毒性肝炎患者的随访特征进行了评估。分别在68例、84例、22例和36例患者中诊断出甲型肝炎(HA)、乙型肝炎(HB)、丙型肝炎(HC)和非甲 - 非丙型肝炎(NON A - C H)。甲型肝炎、乙型肝炎、丙型肝炎和非甲 - 非丙型肝炎患者中分别约有20.6%、19%、45.5%和25%出现肝炎后综合征。三个月时,甲型肝炎、乙型肝炎、丙型肝炎和非甲 - 非丙型肝炎患者的恢复率分别约为61.7%、69%、13.6%和63.9%。除乙型肝炎外,性别、年龄和急性期严重程度等因素对所有类型的迁延率均无影响。六个月后,甲型肝炎、乙型肝炎、丙型肝炎、非甲 - 非丙型肝炎患者中疾病仍处于活动期的比例分别为1.5%、6%、69%、8.3%。除乙型肝炎外,性别、年龄、急性期严重程度等因素对不同类型的慢性化率均无影响。在慢性乙型肝炎病例中,男性、老年人以及急性期症状较轻者更为常见。糖尿病在慢性乙型肝炎病例中也更为常见。谷丙转氨酶(ALT)升高呈平坦型在慢性乙型肝炎和非甲 - 非丙型肝炎病例中更为常见。

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