Kharoubi S
CHU IBN Rochd, Service O.R.L., Annaba, Algérie.
Rev Laryngol Otol Rhinol (Bord). 1998;119(2):109-13.
The case history of a patient with orofacial oedema is presented, together with the findings on extensive investigation. A diagnosis of Melkersson-Rosenthal syndrome (MRS) was made. This case demonstrated the difficulties in diagnosis in monosymptomatic cases, and the importance of further investigation (EMG). MRS is a rare condition with a triad of symptoms: orofacial oedema, facial palsy, and plicated or "scrotal" tongue. The pathogenesis is unknown. The vital prognosis is good. Treatment has not been specific. It relies on local (intra-lesional) and systemic steroids, and elective eyelid surgery. Clofamizine has proved an effective alternative treatment.
本文介绍了一名患有口面部水肿患者的病史，以及广泛检查的结果。诊断为梅尔克森 - 罗森塔尔综合征（MRS）。该病例展示了单症状病例诊断的困难，以及进一步检查（肌电图）的重要性。MRS是一种罕见疾病，具有三联征症状：口面部水肿、面瘫和皱襞舌或“阴囊舌”。其发病机制尚不清楚。重要预后良好。治疗尚无特效方法。主要依靠局部（病灶内）和全身使用类固醇，以及选择性眼睑手术。氯法齐明已被证明是一种有效的替代治疗方法。
