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一项使用模型拟合对面部前后和垂直比例进行的遗传学研究。

A genetic study of anteroposterior and vertical facial proportions using model-fitting.

作者信息

Savoye I, Loos R, Carels C, Derom C, Vlietinck R

机构信息

School of Dentistry, Oral Pathology and Maxillofacial Surgery, Department of Orthodontics, Catholic University of Leuven, Belgium.

出版信息

Angle Orthod. 1998 Oct;68(5):467-70. doi: 10.1043/0003-3219(1998)068<0467:AGSOAA>2.3.CO;2.

Abstract

Genetic model-fitting was used to determine the heritability of anteroposterior and vertical facial proportions in twins. Lateral headplates of 33 monozygotic and 46 dizygotic twins, none of whom had undergone orthodontic treatment, were used. Five proportions, based on four vertical and five horizontal measurements, were assessed: lower facial height, anterior- to posterior-facial height, total facial height to face depth, sella-A-point to sella-B-point, and sella-upper incisal edge to sella-lower incisal edge. Reproducibility was high for all variables. Model-fitting indicated that all the facial proportions were controlled by additive genes and the specific environment. The genetic component was 71% for upper-to lower-facial height, 66% for anterior- to posterior-facial height, 62% for total facial height, and 66% for sella-A-point to sella-B-point and sella-upper incisal edge to sella-lower incisal edge.

摘要

采用遗传模型拟合来确定双胞胎前后面部比例和垂直面部比例的遗传度。使用了33对同卵双胞胎和46对异卵双胞胎的侧位头影测量片,他们均未接受过正畸治疗。基于4项垂直测量和5项水平测量评估了5个比例:面下高、面高前后比、全面高与面深比、蝶鞍点至A点与蝶鞍点至B点的距离、蝶鞍点至上切缘与蝶鞍点至下切缘的距离。所有变量的重复性都很高。模型拟合表明,所有面部比例均受加性基因和特定环境的控制。面高上下比的遗传成分占71%,面高前后比为66%,全面高为62%,蝶鞍点至A点与蝶鞍点至B点的距离以及蝶鞍点至上切缘与蝶鞍点至下切缘的距离均为66%。

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