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来自美味柑橘的一种吡喃香豆素和两种生物碱(其中一种具有解痉作用)。

A pyranocoumarin and two alkaloids (one with antispasmodic effect) from Citrus deliciosa.

作者信息

el-Shafae A M, Soliman A S

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Egypt.

出版信息

Pharmazie. 1998 Sep;53(9):640-3.

PMID:9770213
Abstract

One pyranocoumarin (xanthyletin, 1) and two acridone alkaloids (2',2'-dimethyl-(pyrano5',6':3:4)-1,5-dihydroxy, 6-methoxy, 10-methylacridone, 3, and citpressine-I, 4), were isolated from the roots of Citrus deliciosa Ten (Rutacea). Their structures were elucidated by spectroscopic methods. Reported 13C NMR assignments of alkaloid 3 have been corrected and those of alkaloid 4 are reported for the first time Alkaloid 3 was found to have antispasmodic effect on isolated ileum segments excised from male rabbits.

摘要

从美味柑橘(芸香科)的根中分离出一种吡喃香豆素(花椒毒素,1)和两种吖啶酮生物碱(2',2'-二甲基-(吡喃并[5',6':3:4])-1,5-二羟基,6-甲氧基,10-甲基吖啶酮,3,以及枸橼辛因-I,4)。通过光谱方法阐明了它们的结构。已对生物碱3报道的13C NMR归属进行了校正,并且首次报道了生物碱4的13C NMR归属。发现生物碱3对从雄性兔子切除的离体回肠段有解痉作用。

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