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多重耐药肠球菌:耐药病原体新时代的曙光。

Multidrug-resistant enterococci: the dawn of a new era in resistant pathogens.

作者信息

Antony S J

机构信息

Texas Oncology PA and Texas Tech University Medical Center, El Paso 79915, USA.

出版信息

J Natl Med Assoc. 1998 Sep;90(9):537-40.

PMID:9770953
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2568292/
Abstract

Resistant enterococci, especially vancomycin-resistant enterococci, have rapidly become an important nosocomial pathogen. They are increasingly prevalent among hospitalized patients, patients with serious chronic illnesses, and immunosuppressed patients. Risk factors identified include previous antibiotics, exposure to contaminated equipment, and close proximity to infected patients. Treatment of multidrug-resistant pathogens has become increasingly difficult, with increased morbidity and mortality in these patients. Strict infection control measures remain the mainstay in the management of these infections.

摘要

耐药肠球菌,尤其是耐万古霉素肠球菌,已迅速成为一种重要的医院病原体。它们在住院患者、患有严重慢性病的患者以及免疫抑制患者中越来越普遍。已确定的危险因素包括先前使用过抗生素、接触受污染的设备以及与感染患者密切接触。多重耐药病原体的治疗变得越来越困难,这些患者的发病率和死亡率都有所增加。严格的感染控制措施仍然是这些感染管理的主要手段。

相似文献

1
Multidrug-resistant enterococci: the dawn of a new era in resistant pathogens.多重耐药肠球菌:耐药病原体新时代的曙光。
J Natl Med Assoc. 1998 Sep;90(9):537-40.
2
Multidrug-resistant Enterococcus faecium. An untreatable nosocomial pathogen.耐多药屎肠球菌。一种无法治疗的医院病原体。
Drugs. 1994 Nov;48(5):678-88. doi: 10.2165/00003495-199448050-00003.
3
Vancomycin-resistant enterococci.耐万古霉素肠球菌。
Crit Care Clin. 2013 Oct;29(4):841-52. doi: 10.1016/j.ccc.2013.06.006.
4
Enterococcal resistance--an overview.肠球菌耐药性——概述
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5
Bloodstream infections with vancomycin-resistant enterococci.耐万古霉素肠球菌血流感染
Arch Intern Med. 1996 Jul 8;156(13):1458-62.
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Phenotypes and genotypes of vancomycin-resistant enterococci isolated during long-term follow-up in a patient with recurrent bacteremia and colonization.在一名复发性菌血症和定植患者长期随访期间分离出的耐万古霉素肠球菌的表型和基因型
J Microbiol Immunol Infect. 2002 Dec;35(4):243-8.
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New antibiotic agents for bloodstream infections.用于治疗血流感染的新型抗生素药物。
Int J Antimicrob Agents. 2008 Nov;32 Suppl 1:S60-5. doi: 10.1016/j.ijantimicag.2008.06.003. Epub 2008 Aug 23.
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Vancomycin-resistant enterococcal bacteremia: comparison of clinical features and outcome between Enterococcus faecium and Enterococcus faecalis.耐万古霉素肠球菌血症:粪肠球菌和屎肠球菌临床特征及结局的比较
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Multidrug-resistant enterococci: a threat to the surgical patient.多重耐药肠球菌:对外科手术患者的一种威胁。
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Vancomycin-resistant enterococci.耐万古霉素肠球菌
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本文引用的文献

1
Manipulation of a hospital antimicrobial formulary to control an outbreak of vancomycin-resistant enterococci.通过调整医院抗菌药物处方集来控制耐万古霉素肠球菌的暴发。
Clin Infect Dis. 1996 Nov;23(5):1020-5. doi: 10.1093/clinids/23.5.1020.
2
A comparison of the effect of universal use of gloves and gowns with that of glove use alone on acquisition of vancomycin-resistant enterococci in a medical intensive care unit.在一个医疗重症监护病房中,比较普遍使用手套和隔离衣与仅使用手套对耐万古霉素肠球菌感染的影响。
Ann Intern Med. 1996 Sep 15;125(6):448-56. doi: 10.7326/0003-4819-125-6-199609150-00004.
3
Increased bactericidal activity as documented by serum bactericidal titers for a triple combination of cell wall active agents against gentamicin-resistant enterococci.针对庆大霉素耐药肠球菌,细胞壁活性剂三联组合的血清杀菌效价所证明的杀菌活性增强。
Scand J Infect Dis. 1995;27(4):401-3. doi: 10.3109/00365549509032740.
4
Effective treatment of multidrug-resistant enterococcal experimental endocarditis with combinations of cell wall-active agents.采用细胞壁活性药物联合治疗耐多药肠球菌实验性心内膜炎的疗效
J Infect Dis. 1996 Apr;173(4):909-13. doi: 10.1093/infdis/173.4.909.
5
Epidemiologic analysis and genotypic characterization of a nosocomial outbreak of vancomycin-resistant enterococci.耐万古霉素肠球菌医院感染暴发的流行病学分析及基因分型特征
J Clin Microbiol. 1993 May;31(5):1280-5. doi: 10.1128/jcm.31.5.1280-1285.1993.
6
Triple combination penicillin-vancomycin-gentamicin for experimental endocarditis caused by a highly penicillin-and glycopeptide-resistant isolate of Enterococcus faecium.三联组合青霉素-万古霉素-庆大霉素用于治疗由一株对青霉素和糖肽类高度耐药的粪肠球菌分离株引起的实验性心内膜炎。
J Infect Dis. 1993 Sep;168(3):681-6. doi: 10.1093/infdis/168.3.681.
7
Nosocomial enterococci resistant to vancomycin--United States, 1989-1993.1989 - 1993年美国医院内耐万古霉素肠球菌
MMWR Morb Mortal Wkly Rep. 1993 Aug 6;42(30):597-9.
8
Nosocomial outbreak due to Enterococcus faecium highly resistant to vancomycin, penicillin, and gentamicin.由对万古霉素、青霉素和庆大霉素高度耐药的屎肠球菌引起的医院感染暴发。
Clin Infect Dis. 1993 Jun;16(6):750-5. doi: 10.1093/clind/16.6.750.
9
Antimicrobial susceptibility testing of enterococci: results of a survey conducted by the United Kingdom National External Quality Assessment Scheme for Microbiology.肠球菌的抗菌药敏试验:英国国家微生物学外部质量评估计划开展的一项调查结果
J Antimicrob Chemother. 1993 Sep;32(3):401-11. doi: 10.1093/jac/32.3.401.
10
Novel antibiotic regimens against Enterococcus faecium resistant to ampicillin, vancomycin, and gentamicin.针对对氨苄西林、万古霉素和庆大霉素耐药的屎肠球菌的新型抗生素治疗方案。
Antimicrob Agents Chemother. 1993 Sep;37(9):1904-8. doi: 10.1128/AAC.37.9.1904.