Section of Infectious Diseases, Department of Internal Medicine and Medical Microbiology, University of Manitoba, 543-645 Bannatyne Ave, Basic Medical Building, Winnipeg, Manitoba R3E 0J9, Canada.
Crit Care Clin. 2013 Oct;29(4):841-52. doi: 10.1016/j.ccc.2013.06.006.
Vancomycin-resistant enterococci (VRE) consist mainly of Enterococcus faecalis and E faecium, the latter mostly hospital-acquired. In addition, E gallinarum and E casseliflavus are intrinsically vancomycin-resistant and are community-acquired. VRE have become common in many hospitals throughout the world and, once established, are very difficult to eradicate. VRE are difficult to treat; therefore, infection control measures in hospitals are of prime importance in preventing the establishment of these pathogens. Most severe VRE infections will need combination therapy because many of the effective antimicrobial agents, when used alone, have only a bacteriostatic effect.
耐万古霉素肠球菌（VRE）主要包括粪肠球菌和屎肠球菌，后者主要为医院获得性。此外，鸡肠球菌和黄色肠球菌固有地对万古霉素具有耐药性，且为社区获得性。VRE 在世界上许多医院已经很常见，一旦建立，就很难根除。VRE 很难治疗；因此，医院中的感染控制措施对于预防这些病原体的建立至关重要。大多数严重的 VRE 感染需要联合治疗，因为许多有效的抗菌药物单独使用时只有抑菌作用。
