González-Jiménez M A, Villanueva-Díaz C A
Electron Microscopy Department, Instituto Nacional de Perinatología, México, D.F., Mexico.
Andrologia. 2006 Feb;38(1):26-30. doi: 10.1111/j.1439-0272.2006.00708.x.
As free stereocilia in semen samples from infertile men could be related to a subclinical chronic infection of the seminal tract, we carried out a retrospective analysis of 14 files of infertile men with stereocilia in semen (group 1) and in two control groups: 30 infertile men from the same study population (group 2) and 40 fertile sperm donors (group 3). Clinical, bacteriological, sonographic and microscopic findings associated with these semen samples were compared. Epididymal cysts were found in two of 14 men in group 1 and in four of 28 in group 2. Positive semen cultures for Chlamydia trachomatis, Mycoplasma hominis or Ureaplasma urealyticum (chi(2) = 8.20; P = 0.002; OR: 7.22) and varicocele (chi(2) = 8.96; P = 0.002; OR: 2.25) were associated to the presence of free stereocilia in semen. These data suggest that a silent chronic infection of the epididymis by C. trachomatis, M. hominis, U. urealyticum and/or inflammation produced by varicocele might be the cause of stereocilia loss in the semen.
由于不育男性精液样本中的游离静纤毛可能与精道的亚临床慢性感染有关，我们对14例精液中有静纤毛的不育男性（第1组）以及两个对照组进行了回顾性分析：来自同一研究人群的30例不育男性（第2组）和40例有生育能力的精子捐献者（第3组）。比较了与这些精液样本相关的临床、细菌学、超声和显微镜检查结果。第1组14名男性中有2名发现附睾囊肿，第2组28名中有4名发现附睾囊肿。沙眼衣原体、人型支原体或解脲脲原体精液培养阳性（χ² = 8.20；P = 0.002；比值比：7.22）以及精索静脉曲张（χ² = 8.96；P = 0.002；比值比：2.25）与精液中游离静纤毛的存在有关。这些数据表明，沙眼衣原体、人型支原体、解脲脲原体对附睾的隐匿性慢性感染和/或精索静脉曲张引起的炎症可能是精液中静纤毛缺失的原因。
