既往吸烟者与髋部骨折风险
Ex-smokers and risk of hip fracture.
作者信息
Forsén L, Bjartveit K, Bjørndal A, Edna T H, Meyer H E, Schei B
机构信息
National Institute of Public Health, Oslo, Norway.
出版信息
Am J Public Health. 1998 Oct;88(10):1481-3. doi: 10.2105/ajph.88.10.1481.
Abstract
OBJECTIVES
The purpose of this study was to examine the reversibility of the effect of smoking on hip fracture incidence rates.
METHODS
A 3-year follow-up cohort study was conducted involving 35,767 adults 50 years of age or older. Of these individuals, 421 suffered a hip fracture.
RESULTS
Among participants less than 75 years of age, the relative risk (RR) of hip fracture was elevated for ex-smokers, even for those who had quit smoking more than 5 years previously (men: RR = 4.4, 95% confidence interval [CI] = 1.2, 15.3; women: RR = 1.3, 95% CI = 0.6, 3.0), but was not as high as that for current smokers (men: RR = 5.0, 95% CI = 1.5, 16.9; women: RR = 1.9, 95% CI = 1.2, 3.1).
CONCLUSIONS
The effect of smoking on risk of hip fracture was not reversed completely 5 years after smoking cessation.
摘要
目的
本研究旨在探讨吸烟对髋部骨折发病率影响的可逆性。
方法
进行了一项为期3年的随访队列研究，纳入35767名50岁及以上的成年人。其中，421人发生了髋部骨折。
结果
在75岁以下的参与者中，既往吸烟者髋部骨折的相对风险（RR）升高，即使是那些戒烟超过5年的人（男性：RR = 4.4，95%置信区间[CI] = 1.2，15.3；女性：RR = 1.3，95% CI = 0.6，3.0），但不如当前吸烟者高（男性：RR = 5.0，95% CI = 1.5，16.9；女性：RR = 1.9，95% CI = 1.2，3.1）。
结论
戒烟5年后，吸烟对髋部骨折风险的影响并未完全逆转。
相似文献
1
Ex-smokers and risk of hip fracture.既往吸烟者与髋部骨折风险
Am J Public Health. 1998 Oct;88(10):1481-3. doi: 10.2105/ajph.88.10.1481.
2
Tobacco smoking and risk of hip fracture in men and women.吸烟与男性和女性髋部骨折风险
Int J Epidemiol. 2000 Apr;29(2):253-9. doi: 10.1093/ije/29.2.253.
3
Smoking, smoking cessation, and risk of hip fracture in women.吸烟、戒烟与女性髋部骨折风险
Am J Med. 1999 Mar;106(3):311-4. doi: 10.1016/s0002-9343(99)00022-4.
4
Risk factors for hip fractures in a middle-aged population: a study of 33,000 men and women.中年人群髋部骨折的风险因素：一项对33000名男性和女性的研究。
Osteoporos Int. 2005 Dec;16(12):2185-94. doi: 10.1007/s00198-005-2006-1. Epub 2005 Sep 22.
5
Risk factors for hip fracture in middle-aged Norwegian women and men.挪威中年女性和男性髋部骨折的风险因素。
Am J Epidemiol. 1993 Jun 1;137(11):1203-11. doi: 10.1093/oxfordjournals.aje.a116622.
6
Interaction between current smoking, leanness, and physical inactivity in the prediction of hip fracture.当前吸烟、消瘦与缺乏身体活动在预测髋部骨折中的相互作用。
J Bone Miner Res. 1994 Nov;9(11):1671-8. doi: 10.1002/jbmr.5650091102.
7
Cigarette smoking, alcohol consumption, and risk of hip fracture in women.女性吸烟、饮酒与髋部骨折风险
Arch Intern Med. 2001 Apr 9;161(7):983-8. doi: 10.1001/archinte.161.7.983.
8
Hormone replacement therapy and hip fracture risk: effect modification by tobacco smoking, alcohol intake, physical activity, and body mass index.激素替代疗法与髋部骨折风险：吸烟、饮酒、身体活动及体重指数的效应修正作用
Am J Epidemiol. 1999 Nov 15;150(10):1085-93. doi: 10.1093/oxfordjournals.aje.a009933.
9
Cigarette smoking and risk of hip fracture in women: a meta-analysis of prospective cohort studies.女性吸烟与髋部骨折风险：前瞻性队列研究的荟萃分析
Injury. 2015 Jul;46(7):1333-40. doi: 10.1016/j.injury.2015.04.008. Epub 2015 Apr 20.
10
[Tobacco smoking and risk of hip fracture in men and women. Results from the Hovedstadens Center for Prospective Population Studies].[吸烟与男性和女性髋部骨折风险。首都前瞻性人口研究中心的结果]
Ugeskr Laeger. 2001 Oct 1;163(40):5532-6.
引用本文的文献
1
Gender differences between smoking and the risk of hip fracture.吸烟与髋部骨折风险之间的性别差异。
J Bone Miner Metab. 2024 Nov;42(6):623-632. doi: 10.1007/s00774-024-01546-y. Epub 2024 Sep 26.
2
Smoking and fracture risk in men: a meta-analysis of cohort studies, using both frequentist and Bayesian approaches.吸烟与男性骨折风险：基于频繁主义和贝叶斯两种方法的队列研究荟萃分析。
Sci Rep. 2022 Jun 3;12(1):9270. doi: 10.1038/s41598-022-13356-1.
3
Modifiable lifestyle factors associated with fragility hip fracture: a systematic review and meta-analysis.与脆性髋部骨折相关的可改变生活方式因素：系统评价和荟萃分析。
J Bone Miner Metab. 2021 Sep;39(5):893-902. doi: 10.1007/s00774-021-01230-5. Epub 2021 May 15.
4
Effect of a Multifactorial Intervention on Fracture in Patients With Type 2 Diabetes: Subanalysis of the J-DOIT3 Study.多因素干预对2型糖尿病患者骨折的影响：J-DOIT3研究的亚组分析
J Clin Endocrinol Metab. 2021 Apr 23;106(5):e2116-e2128. doi: 10.1210/clinem/dgab013.
5
Current and former smokers and hip fractures.当前吸烟者和既往吸烟者与髋部骨折
J Frailty Sarcopenia Falls. 2018 Sep 1;3(3):148-154. doi: 10.22540/JFSF-03-148. eCollection 2018 Sep.
6
Effect of Cigarette Smoking on Risk of Hip Fracture in Men: A Meta-Analysis of 14 Prospective Cohort Studies.吸烟对男性髋部骨折风险的影响：14项前瞻性队列研究的荟萃分析
PLoS One. 2016 Dec 30;11(12):e0168990. doi: 10.1371/journal.pone.0168990. eCollection 2016.
7
Smoking and body fat mass in relation to bone mineral density and hip fracture: the Hordaland Health Study.吸烟和体脂量与骨矿物质密度及髋部骨折的关系：霍达兰健康研究
PLoS One. 2014 Mar 25;9(3):e92882. doi: 10.1371/journal.pone.0092882. eCollection 2014.
8
The effects of smoking on bone metabolism.吸烟对骨代谢的影响。
Osteoporos Int. 2012 Aug;23(8):2081-92. doi: 10.1007/s00198-012-1940-y. Epub 2012 Feb 21.
9
Mental distress and risk of hip fracture. Do broken hearts lead to broken bones?精神困扰与髋部骨折风险。心碎会导致骨折吗？
J Epidemiol Community Health. 1999 Jun;53(6):343-7. doi: 10.1136/jech.53.6.343.
本文引用的文献
1
A meta-analysis of cigarette smoking, bone mineral density and risk of hip fracture: recognition of a major effect.吸烟、骨密度与髋部骨折风险的荟萃分析：对主要影响的认识
BMJ. 1997 Oct 4;315(7112):841-6. doi: 10.1136/bmj.315.7112.841.
2
Androgens and their role in skeletal homeostasis.
Horm Res. 1996;46(2):95-8. doi: 10.1159/000185003.
3
Risk factors for hip fracture in middle-aged Norwegian women and men.挪威中年女性和男性髋部骨折的风险因素。
Am J Epidemiol. 1993 Jun 1;137(11):1203-11. doi: 10.1093/oxfordjournals.aje.a116622.
4
Human giant cell tumors of the bone (osteoclastomas) are estrogen target cells.人骨巨细胞瘤（破骨细胞瘤）是雌激素靶细胞。
Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5227-31. doi: 10.1073/pnas.91.12.5227.
5
Case-control study of risk factors for hip fractures in the elderly.老年人髋部骨折危险因素的病例对照研究。
Am J Epidemiol. 1994 Mar 1;139(5):493-503. doi: 10.1093/oxfordjournals.aje.a117032.
6
Time-related increase of biochemical markers of bone turnover in androgen-deficient male rats.雄激素缺乏雄性大鼠骨转换生化标志物随时间的增加
Bone Miner. 1994 Aug;26(2):123-31. doi: 10.1016/s0169-6009(08)80057-8.
7
Interaction between current smoking, leanness, and physical inactivity in the prediction of hip fracture.当前吸烟、消瘦与缺乏身体活动在预测髋部骨折中的相互作用。
J Bone Miner Res. 1994 Nov;9(11):1671-8. doi: 10.1002/jbmr.5650091102.
8
Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group.白人女性髋部骨折的危险因素。骨质疏松性骨折研究组研究。
N Engl J Med. 1995 Mar 23;332(12):767-73. doi: 10.1056/NEJM199503233321202.
9
New insights into the cellular, biochemical, and molecular basis of postmenopausal and senile osteoporosis: roles of IL-6 and gp130.
Int J Immunopharmacol. 1995 Feb;17(2):109-16. doi: 10.1016/0192-0561(94)00089-7.
10
Effects of smoking on testicular function, semen quality and sperm fertilizing capacity.
J Urol. 1995 Sep;154(3):1030-4.
Zotero 插件