Palanduz S, Aktan M, Ozturk S, Tutkan G, Cefle K, Pekcelen Y
Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Turkey.
Cancer Genet Cytogenet. 1998 Oct 1;106(1):76-7. doi: 10.1016/s0165-4608(98)00032-6.
A case of acute myelomonocytic leukemia (AMMoL; M4) with a 47,XYY karyotype is reported. This chromosome aneuploidy was found in both bone marrow cells and mitogen-stimulated lymphocytes. The contribution of XYY chromosomal constitution in the pathogenesis of AMMoL is controversial.
报告了一例核型为47,XYY的急性粒单核细胞白血病（AMMoL；M4）病例。在骨髓细胞和丝裂原刺激的淋巴细胞中均发现了这种染色体非整倍体。XYY染色体构成在AMMoL发病机制中的作用存在争议。
