Perez de Oteyza J, Sureda A, Ferro T, Laraña J G, Odriozola J, Escribano L, Navarro J L
Department of Hematology, Hospital Ramon y Cajal, Madrid, Spain.
Cancer Genet Cytogenet. 1990 Oct 15;49(2):225-7. doi: 10.1016/0165-4608(90)90145-z.
A case of acute lymphoblastic leukemia (ALL) in a 16-year-old male with a 47,XYY karyotype is reported. This chromosome aneuploidy was found in both bone marrow (BM) cells and mitogen-stimulated lymphocytes. Immunologic profile of leukemic cells showed a null phenotype. To our knowledge, this is the fifth case reported in the literature.
报告了一例16岁男性急性淋巴细胞白血病（ALL）患者，其核型为47,XYY。在骨髓（BM）细胞和丝裂原刺激的淋巴细胞中均发现了这种染色体非整倍性。白血病细胞的免疫表型显示为无表型。据我们所知，这是文献中报道的第五例。
