Rubaltelli F F, Biadaioli R, Pecile P, Nicoletti P
Department of Pediatrics, Careggi University Hospital, Florence, Italy.
J Perinat Med. 1998;26(3):186-91. doi: 10.1515/jpme.1998.26.3.186.
We verified whether an adapted formula, which presents poly-oligosaccharides containing maltose, promotes intestinal implantation of bacterial microflora to the extent that breast milk does, as an epidemiological link exists between newborn feeding methods and infant health. Stool specimens were taken and cultured at the fourth day of life from vaginally born neonates. Twenty-two were breast-fed and 20 were fed with formula. In breast-fed infants, the Bifidobacterium was significantly prevalent expressed in percentage (47.6% vs 15%) and in mean bacterial fecal counts/g (7.1 +/- 0.8 vs 5.3 +/- 0.6). Enterococci prevailed in formula-fed infants (mean counts 6.7 +/- 0.9 vs 7.4 +/- 0.5). Of interest is the significant and simultaneous presence of Bifidobacteria and Bacteroides in breast-fed infants. Our study indicates that flora with a diet-dependent pattern is present from the fourth day of life. These results support a preference for breast feeding over formula feeding, even though renewed.
鉴于新生儿喂养方式与婴儿健康之间存在流行病学关联，我们验证了一种含有麦芽糖的多元低聚糖的改良配方奶粉，是否能像母乳一样促进肠道细菌微生物群的定植。对经阴道分娩的新生儿在出生后第四天采集粪便样本并进行培养。22名婴儿采用母乳喂养，20名婴儿采用配方奶粉喂养。在母乳喂养的婴儿中，双歧杆菌在百分比（47.6%对15%）和每克粪便细菌平均计数（7.1±0.8对5.3±0.6）方面均显著占优势。肠球菌在配方奶粉喂养的婴儿中占优势（平均计数6.7±0.9对7.4±0.5）。值得关注的是，母乳喂养的婴儿中同时显著存在双歧杆菌和拟杆菌。我们的研究表明，从出生后第四天起就存在依赖饮食模式的菌群。这些结果支持了即使是再次提倡母乳喂养也优于配方奶粉喂养的观点。
