Leung W K, Chan F K, Falk M S, Suen R, Sung J J
Departments of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong.
J Clin Microbiol. 1998 Nov;36(11):3441-2. doi: 10.1128/JCM.36.11.3441-3442.1998.
Consecutive Chinese patients undergoing endoscopy for dyspepsia were tested for Helicobacter pylori infection by two rapid whole-blood tests: FlexPack HP (Abbott Laboratories) and Helisal One-Step (Cortecs Diagnostics). Biopsy-based tests (rapid urease test and histology) and the [13C]urea breath test were used as the "gold standard." One hundred sixty-one consecutive patients were studied, and 88 (54.7%) were confirmed to have H. pylori infection. The sensitivities, specificities, and positive and negative predictive values were 81.8%, 83.6% (P = 0.008), 85.7% (P = 0.04), and 79.2% for FlexPack HP and 84.1%, 63.0% (P = 0.008), 73.3% (P = 0.047), and 76.7% for Helisal One-Step, respectively.
对因消化不良接受内镜检查的连续中国患者,采用两种快速全血检测法检测幽门螺杆菌感染:FlexPack HP(雅培实验室)和Helisal一步法(科泰克斯诊断公司)。基于活检的检测方法(快速尿素酶试验和组织学检查)以及[13C]尿素呼气试验被用作“金标准”。对161例连续患者进行了研究,其中88例(54.7%)被证实感染幽门螺杆菌。FlexPack HP的敏感性、特异性、阳性预测值和阴性预测值分别为81.8%、83.6%(P = 0.008)、85.7%(P = 0.04)和79.2%,Helisal一步法的相应数值分别为84.1%、63.0%(P = 0.008)、73.3%(P = 0.047)和76.7%。