Sequence of the cry11Bb11 gene from Bacillus thuringiensis subsp. medellin and toxicity analysis of its encoded protein.

作者信息

Orduz S, Realpe M, Arango R, Murillo L A, Delécluse A

机构信息

Unidad de Biotecnología y Control Biológico, Corporación para Investigaciones Biológicas, Apartado Aéreo 7378, Medellín, Colombia.

出版信息

Biochim Biophys Acta. 1998 Oct 14;1388(1):267-72. doi: 10.1016/s0167-4838(98)00168-x.

The nucleotide sequence of the cry11Bb1 gene from Bacillus thuringiensis subsp. medellin was determined. The corresponding protein has a deduced molecular mass of 88.2 kDa, and is 60.9% and 83% identical to the proteins Cry11Aa1 and Cry11Ba1, respectively. The Cry11Bb1 protein contains five repetitive blocks of 16 amino acids at the C terminal part. It is highly toxic to first instar laboratory reared Aedes aegypti, Anopheles albimanus and Culex quinquefasciatus larvae.