Cunliffe I A, Molteno A C
Department of Ophthalmology, University of Otago Medical School, Dunedin Hospital, New Zealand.
Eye (Lond). 1998;12 ( Pt 3a):379-85. doi: 10.1038/eye.1998.90.
This study reviews the long-term follow-up (mean 11.2 years, range 9 months to 16 years 9 months) of Molteno drains used in the treatment of glaucoma presenting in childhood, in 34 eyes of 25 patients.
Intraocular pressure control was achieved in 85% of eyes, and vision (where measurable) was maintained in 57% of eyes. Seventy-one per cent of eyes required further surgical intervention. Thirty-two per cent of these cases were for drain-related problems, which may be avoidable with the use of current surgical techniques. The remaining interventions were for associated ocular defects, and for problems caused by multiple surgical procedures and periods of high intraocular pressure during early childhood.
Today the implants are used at an earlier stage in the disease process to try to obtain early and definitive IOP control and so help to optimise the long-term visual prognosis.
本研究回顾了25例患者34只眼使用莫尔托诺引流管治疗儿童青光眼的长期随访情况（平均11.2年，范围9个月至16年9个月）。
85%的患眼眼压得到控制，57%的患眼（视力可测量时）视力得以维持。71%的患眼需要进一步手术干预。其中32%的病例是与引流管相关的问题，采用当前手术技术或许可以避免。其余干预是针对相关眼部缺陷，以及儿童早期多次手术和高眼压期所导致的问题。
如今，在疾病进程的早期阶段就使用植入物，试图早期且确切地控制眼压，从而有助于优化长期视觉预后。
