Sharma H S, Abdullah J M, Othman N H, Muhamad M
Department of Otorhinolaryngology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
J Laryngol Otol. 1998 Jul;112(7):682-6. doi: 10.1017/s0022215100141453.
Sinonasal teratocarcinosarcoma is very unusual malignant neoplasm histologically consisting of an epithelial element and one or more mesenchymal components. This is a report of teratocarcinosarcoma, in a 74-year-old male, involving the right nasal cavity and ethmoids with intracranial extension. The tumour was totally resected via the craniofacial approach and the patient was given post-operative chemotherapy. Extensive tumour necrosis, rapid growth and local destruction are the prominent features of this tumour. The clinical presentation, pathological features and clinical course of this rare malignancy are discussed with a review of the literature.
鼻窦畸胎癌肉瘤是一种非常罕见的恶性肿瘤,组织学上由上皮成分和一个或多个间叶成分组成。本文报告一例74岁男性的畸胎癌肉瘤,累及右侧鼻腔和筛窦并向颅内扩展。肿瘤通过颅面联合入路完全切除,患者术后接受了化疗。广泛的肿瘤坏死、快速生长和局部破坏是该肿瘤的突出特征。本文结合文献复习讨论了这种罕见恶性肿瘤的临床表现、病理特征及临床病程。