Shindo M L, Stanley R B, Kiyabu M T
Department of Otolaryngology-Head & Neck Surgery, University of Southern California, Los Angeles.
Head Neck. 1990 Nov-Dec;12(6):516-9. doi: 10.1002/hed.2880120613.
Malignant neoplasms consisting of an epithelial element and 1 or more nesenchymal components are variously termed teratocarcinosarcoma, carcinosarcoma, malignant teratoma, spindle cell carcinoma, and pseudosarcomatous squamous cell carcinoma. Carcinosarcoma, consisting of a malignant epithelial element and a single malignant mesenchymal component, is extremely rare in the sinonasal tract. We report a case of carcinosarcoma involving the nasal cavity, paranasal sinuses, and anterior cranial fossa. Rapid growth and extensive local destruction are prominent features of this tumor, emphasizing the need for early diagnosis and prompt institution of aggressive therapy. The clinical presentation, pathologic features, and clinical course are detailed.
由上皮成分和一个或多个间充质成分组成的恶性肿瘤有多种称谓，包括畸胎癌肉瘤、癌肉瘤、恶性畸胎瘤、梭形细胞癌和假肉瘤性鳞状细胞癌。癌肉瘤由恶性上皮成分和单一恶性间充质成分组成，在鼻窦区域极为罕见。我们报告一例累及鼻腔、鼻窦和前颅窝的癌肉瘤病例。快速生长和广泛的局部破坏是该肿瘤的突出特征，这凸显了早期诊断和及时采取积极治疗的必要性。本文详细介绍了其临床表现、病理特征及临床病程。
