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丙烯酸骨水泥的断裂特性。I. 断裂韧性。

Fracture characteristics of acrylic bone cements. I. Fracture toughness.

作者信息

Freitag T A, Cannon S L

出版信息

J Biomed Mater Res. 1976 Sep;10(5):805-28. doi: 10.1002/jbm.820100512.

Abstract

The vital first phase of the overall materials study to protract the life of the total joint replacements is the identification of the fracture toughness and fatigue properties of bone cements. Information gained from fatigue testing, performed in a manner which simmulates in vivo conditions, and fracture toughness, which is a measure of the propensity of a crack to propagate, is the first step towards the prediction of the life of the total joint replacement. This study is concerned with the fracture toughness of Zimmer and Simplex-P cold-curing bone cements. Following cement fabrication conditions which closely approximate clinical procedures, fracture toughness testing was conducted on cement specimens which were immersed in bovine serum at 37 degrees C in order to simulate in vivo conditions. In addition, a similar study was completed on specimens, tested in air at ambient temperature for purposes of comparison. Results of this procedure, when analyzed by a Student's t-test at the 95% confidence level with eight degrees of freedom, indicate that both Zimmer and Simplex-P exhibit a higher fracture toughness in the simulated physiological environment. In order to determine whether the addition of barium sulfate to these cements compromises the fracture toughness, the above described testing rationale was repeated, indicating the existence of a complicated relationship between the different testing environments and barium sulfate. The importance of these results lies in the fact that an increased fracture toughness indicates that a cement will inherently exhibit a greater degree of resistance to the propagation of cracks, which could contribute to the ultimate failure of the total joint replacement.

摘要

为延长全关节置换假体的使用寿命而进行的整体材料研究的关键第一步,是确定骨水泥的断裂韧性和疲劳性能。通过以模拟体内条件的方式进行疲劳测试所获得的信息,以及作为裂纹扩展倾向度量的断裂韧性,是迈向预测全关节置换假体寿命的第一步。本研究关注的是Zimmer和Simplex-P冷固化骨水泥的断裂韧性。按照与临床程序非常接近的水泥制备条件,对浸泡在37摄氏度牛血清中的水泥试样进行断裂韧性测试,以模拟体内条件。此外,为作比较,还对在室温空气中测试的试样完成了一项类似研究。当以自由度为8的95%置信水平通过学生t检验分析该程序的结果时,表明Zimmer和Simplex-P在模拟生理环境中均表现出更高的断裂韧性。为了确定向这些水泥中添加硫酸钡是否会损害断裂韧性,重复了上述测试原理,结果表明不同测试环境与硫酸钡之间存在复杂关系。这些结果的重要性在于,断裂韧性增加表明水泥本身将对裂纹扩展表现出更大程度的抗性,而裂纹扩展可能导致全关节置换假体最终失效。

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