Vaidya B, Coulthard A, Goonetilleke A, Burn D J, James R A, Kendall-Taylor P
Department of Medicine (Endocrinology), Royal Victoria Infirmary, Newcastle-upon-Tyne, United Kingdom.
Thyroid. 1998 Sep;8(9):787-90. doi: 10.1089/thy.1998.8.787.
Riedel's invasive fibrous thyroiditis (IFT) is a rare disease of unknown etiology characterized by a dense fibrosis involving the thyroid gland and its surrounding tissues. Clinically, patients present with a stony hard goiter frequently associated with compressive symptoms. Involvement of the surrounding neck structures by IFT can lead to various clinical sequelae. We report the case of a 55-year-old woman with known IFT who developed thrombosis in the right internal jugular vein that progressed to the right sigmoid, transverse, and superior sagittal sinuses. IFT could have predisposed to cerebral venous sinus thrombosis by causing venous stasis, vascular damage and possibly a hypercoagulable state. To our knowledge, this is the first report of cerebral venous sinus thrombosis that developed as a complication of IFT.
里德尔侵袭性纤维性甲状腺炎（IFT）是一种病因不明的罕见疾病，其特征是甲状腺及其周围组织出现致密纤维化。临床上，患者表现为质地坚硬的甲状腺肿，常伴有压迫症状。IFT累及颈部周围结构可导致各种临床后遗症。我们报告一例55岁已知患有IFT的女性病例，该患者右侧颈内静脉发生血栓形成，并进展至右侧乙状窦、横窦和上矢状窦。IFT可能通过导致静脉淤滞、血管损伤以及可能的高凝状态而引发脑静脉窦血栓形成。据我们所知，这是首例作为IFT并发症发生的脑静脉窦血栓形成的报告。
