Hermans Ellen, Mariën Peter, De Deyn Peter P
Department of Neurology and Memory Clinic, Middelheim and Hoge Beuken General Hospitals (ZNA), and Reference Center for Biological Markers of Memory Disorders, Laboratory of Neurochemistry and Behavior, Institute Born-Bunge, University of Antwerp, Antwerp, Brussels, Belgium.
Case Rep Neurol. 2011 Sep;3(3):203-9. doi: 10.1159/000331448. Epub 2011 Sep 7.
Cerebral venous thrombosis (CVT) is a distinct cerebrovascular condition that represents 0.5-1% of all strokes in the general population. Because of its procoagulant and antifibrinolytic effects [Horne et al.: J Clin Endocrinol Metab 2004;89:4469-4473], hyperthyroidism has been proposed as a predisposing factor for CVT [Saposnik et al.: Stroke 2011;42:1158-1192]. For the first time, we describe a 22-year-old right-handed woman with a sinus sigmoideus thrombosis due to Graves' disease. Although subclinical hyperthyroidism had been detected 2 years before the onset of neurological symptoms, she did not receive any medical follow-up. Early recognition, diagnosis and treatment are of crucial importance, as Graves' disease is a risk factor for CVT and stroke.
脑静脉血栓形成（CVT）是一种独特的脑血管疾病，在普通人群中占所有中风的0.5%-1%。由于甲状腺功能亢进症具有促凝和抗纤维蛋白溶解作用[霍恩等人：《临床内分泌与代谢杂志》2004年；89:4469-4473]，因此有人提出甲状腺功能亢进症是CVT的一个诱发因素[萨波斯尼克等人：《中风》2011年；42:1158-1192]。我们首次描述了一名22岁的右利手女性，因格雷夫斯病导致乙状窦血栓形成。尽管在神经症状出现前2年就检测到了亚临床甲状腺功能亢进症，但她没有接受任何医学随访。早期识别、诊断和治疗至关重要，因为格雷夫斯病是CVT和中风的一个危险因素。
