• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Severe selective IgM deficiency.严重选择性IgM缺乏症。
J Clin Pathol. 1976 Sep;29(9):773-7. doi: 10.1136/jcp.29.9.773.
2
[Clinical and immunological aspects of type I dysgammaglobulinemia].[Ⅰ型免疫球蛋白异常血症的临床与免疫学方面]
Union Med Can. 1975 Mar;104(3):393-5.
3
[Deficiency and lack of immunoglobulin A (IgA). Study of 12 cases].[免疫球蛋白A（IgA）缺乏症。12例病例研究]
Rev Clin Esp. 1976 Jul 31;142(2):135-9.
4
Selective deficiency of IgG and IgA as a first stage defect in B cell differentiation.IgG和IgA选择性缺乏作为B细胞分化的初始阶段缺陷
Blut. 1977 Mar;34(3):197-200. doi: 10.1007/BF00996168.
5
Selective immunoglobulin M deficiency in foals.幼驹的选择性免疫球蛋白M缺乏症。
J Am Vet Med Assoc. 1977 Jan 15;170(2):212-5.
6
A case of sex-linked hereditary dysgammaglobulinaemia accompanied by interstitial pneumonia and lasting neutropenia.
Ann Immunol Hung. 1972;16(0):295-301.
7
[Proceedings: Malabsorption and primary immunoglobulin A deficiency. Apropos of a case without atrophy and with villous atrophy].[会议论文：吸收不良与原发性免疫球蛋白A缺乏症。关于一例无萎缩及绒毛萎缩的病例]
Arch Fr Mal App Dig. 1975 Apr-May;64(3):276-7.
8
[IgM antibody deficiency with normal serum IgM concentration in a family (author's transl)].一个家族中血清IgM浓度正常的IgM抗体缺乏症（作者译）
Padiatr Padol. 1975;10(2):151-4.
9
Primary selective deficiency of immunoglobulin M.免疫球蛋白M原发性选择性缺乏症
Aust N Z J Med. 1978 Aug;8(4):436-8. doi: 10.1111/j.1445-5994.1978.tb04920.x.
10
[IgA deficiency: Clinical analysis].[免疫球蛋白A缺乏症：临床分析]
Rev Chil Pediatr. 1976 May-Jun;47(3):217-23.

引用本文的文献

1
Selective IgM deficiency: evaluation of 75 patients according to different diagnostic criteria.选择性IgM缺乏症：根据不同诊断标准对75例患者的评估
Immunol Res. 2024 Dec 16;73(1):15. doi: 10.1007/s12026-024-09568-4.
2
Selective IgM Deficiency: Evidence, Controversies, and Gaps.选择性IgM缺乏症：证据、争议与空白
Diagnostics (Basel). 2023 Sep 4;13(17):2861. doi: 10.3390/diagnostics13172861.
3
Selective immunoglobulin M deficiency in a patient with celiac disease and recurrent pneumonia.一名患有乳糜泻和复发性肺炎患者的选择性免疫球蛋白M缺乏症
Clin Case Rep. 2020 Dec 18;9(1):158-163. doi: 10.1002/ccr3.3489. eCollection 2021 Jan.
4
Truly selective primary IgM deficiency is probably very rare.真正选择性的 IgM 缺乏症可能非常罕见。
Clin Exp Immunol. 2018 Feb;191(2):203-211. doi: 10.1111/cei.13065. Epub 2017 Oct 27.
5
Selective IgM Deficiency-An Underestimated Primary Immunodeficiency.选择性IgM缺乏症——一种被低估的原发性免疫缺陷病。
Front Immunol. 2017 Sep 5;8:1056. doi: 10.3389/fimmu.2017.01056. eCollection 2017.
6
Selective IgM Deficiency: Clinical and Laboratory Features of 17 Patients and a Review of the Literature.选择性 IgM 缺陷：17 例患者的临床和实验室特征及文献复习。
J Clin Immunol. 2017 Aug;37(6):559-574. doi: 10.1007/s10875-017-0420-8. Epub 2017 Jul 21.
7
Primary selective IgM deficiency: an ignored immunodeficiency.原发性选择性IgM缺乏症：一种被忽视的免疫缺陷病。
Clin Rev Allergy Immunol. 2014 Apr;46(2):104-11. doi: 10.1007/s12016-013-8375-x.
8
Pediatric selective IgM immunodeficiency.小儿选择性IgM免疫缺陷
Clin Dev Immunol. 2008;2008:624850. doi: 10.1155/2008/624850. Epub 2008 Nov 24.
9
Selective immunoglobulin M deficiency associated with disseminated molluscum contagiosum.与播散性传染性软疣相关的选择性免疫球蛋白M缺乏症
Eur J Pediatr. 1986 Apr;145(1-2):99-103. doi: 10.1007/BF00441866.
10
Selective partial IgM deficiency: functional assessment of T and B lymphocytes in vitro.选择性部分 IgM 缺乏症：T 淋巴细胞和 B 淋巴细胞的体外功能评估
J Clin Immunol. 1986 Mar;6(2):130-5. doi: 10.1007/BF00918745.

本文引用的文献

1
QUANTITATIVE DETERMINATION OF SERUM IMMUNOGLOBULINS IN ANTIBODY-AGAR PLATES.抗体琼脂平板中血清免疫球蛋白的定量测定
J Immunol. 1965 Jan;94:84-90.
2
Metabolic heterogeneity of human gamma-globulin.人γ-球蛋白的代谢异质性
Biochem J. 1960 Sep;76(3):475-87. doi: 10.1042/bj0760475.
3
[Congenital immunological paresis in the absence of specific beta 2-globulin & normal quantities of gamma-globulin].
Helv Paediatr Acta. 1957 Aug;12(3):241-59.
4
Development of gamma G, gamma A, gamma M, beta IC-beta IA, C 1 esterase inhibitor, ceruloplasmin, transferrin, hemopexin, haptoglobin, fibrinogen, plasminogen, alpha 1-antitrypsin, orosomucoid, beta-lipoprotein, alpha 2-macroglobulin, and prealbumin in the human conceptus.人类胚胎中γG、γA、γM、βIC-βIA、C1酯酶抑制剂、铜蓝蛋白、转铁蛋白、血红素结合蛋白、触珠蛋白、纤维蛋白原、纤溶酶原、α1-抗胰蛋白酶、类粘蛋白、β-脂蛋白、α2-巨球蛋白和前白蛋白的发育情况。
J Clin Invest. 1969 Aug;48(8):1433-46. doi: 10.1172/JCI106109.
5
Deficiency of IgM.IgM缺乏
Pediatrics. 1971 Feb;47(2):399-404.
6
Immunoglobulin M in meningococcemia.
N Y State J Med. 1970 Jun 1;70(11):1298-9.
7
Chronic meningococcemia. Possible pathogenic role of IgM deficiency.慢性脑膜炎球菌血症。IgM缺乏的可能致病作用。
Arch Intern Med. 1972 Dec;130(6):943-6. doi: 10.1001/archinte.130.6.943.
8
Three cases of meningococcal infection in a family, associated with a deficient immune response.一个家庭中出现三例脑膜炎球菌感染病例，与免疫反应缺陷有关。
Arch Dis Child. 1973 Sep;48(9):742-3. doi: 10.1136/adc.48.9.742.
9
Lymphocyte transformation using whole blood cultures: an analysis of responses.使用全血培养进行淋巴细胞转化：反应分析
J Immunol Methods. 1972 Nov;2(1):99-114. doi: 10.1016/0022-1759(72)90022-1.
10
Leukopenia, leukoagglutinins, and low IgM in a family with severe febrile illnesses.一个患有严重发热性疾病的家族中的白细胞减少、白细胞凝集素和低IgM 。
Clin Immunol Immunopathol. 1973 Jan;1(2):220-9. doi: 10.1016/0090-1229(73)90022-6.

严重选择性IgM缺乏症。

Severe selective IgM deficiency.

作者信息

Ross I N, Thompson R A

出版信息

J Clin Pathol. 1976 Sep;29(9):773-7. doi: 10.1136/jcp.29.9.773.

DOI:10.1136/jcp.29.9.773
PMID:977778
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC476177/
Abstract

Among the primary antibody deficiency syndromes, severe selective IgM deficiency (also previously known as type V dysgammaglobulinaemia) is rare, and the majority of previous reports have indicated a fatal outcome. Three adult patients who were found to have a persistently low serum IgM are described. This deficiency was not obviously related to their presenting illness; in two of the patients, who were investigated in detail, it appeared to be of no immediate consequence.

摘要

在原发性抗体缺陷综合征中，严重选择性IgM缺乏症（以前也称为V型免疫球蛋白异常血症）较为罕见，以往大多数报告表明其预后不良。本文描述了三名成年患者，他们的血清IgM持续偏低。这种缺乏与他们当前的疾病并无明显关联；在其中两名接受详细检查的患者中，这种缺乏似乎并无直接影响。