严重选择性IgM缺乏症。
Severe selective IgM deficiency.
作者信息
Ross I N, Thompson R A
出版信息
J Clin Pathol. 1976 Sep;29(9):773-7. doi: 10.1136/jcp.29.9.773.
Abstract
Among the primary antibody deficiency syndromes, severe selective IgM deficiency (also previously known as type V dysgammaglobulinaemia) is rare, and the majority of previous reports have indicated a fatal outcome. Three adult patients who were found to have a persistently low serum IgM are described. This deficiency was not obviously related to their presenting illness; in two of the patients, who were investigated in detail, it appeared to be of no immediate consequence.
摘要
在原发性抗体缺陷综合征中，严重选择性IgM缺乏症（以前也称为V型免疫球蛋白异常血症）较为罕见，以往大多数报告表明其预后不良。本文描述了三名成年患者，他们的血清IgM持续偏低。这种缺乏与他们当前的疾病并无明显关联；在其中两名接受详细检查的患者中，这种缺乏似乎并无直接影响。
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本文引用的文献
1
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J Immunol. 1965 Jan;94:84-90.
2
Metabolic heterogeneity of human gamma-globulin.人γ-球蛋白的代谢异质性
Biochem J. 1960 Sep;76(3):475-87. doi: 10.1042/bj0760475.
3
[Congenital immunological paresis in the absence of specific beta 2-globulin & normal quantities of gamma-globulin].
Helv Paediatr Acta. 1957 Aug;12(3):241-59.
4
Development of gamma G, gamma A, gamma M, beta IC-beta IA, C 1 esterase inhibitor, ceruloplasmin, transferrin, hemopexin, haptoglobin, fibrinogen, plasminogen, alpha 1-antitrypsin, orosomucoid, beta-lipoprotein, alpha 2-macroglobulin, and prealbumin in the human conceptus.人类胚胎中γG、γA、γM、βIC-βIA、C1酯酶抑制剂、铜蓝蛋白、转铁蛋白、血红素结合蛋白、触珠蛋白、纤维蛋白原、纤溶酶原、α1-抗胰蛋白酶、类粘蛋白、β-脂蛋白、α2-巨球蛋白和前白蛋白的发育情况。
J Clin Invest. 1969 Aug;48(8):1433-46. doi: 10.1172/JCI106109.
5
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Pediatrics. 1971 Feb;47(2):399-404.
6
Immunoglobulin M in meningococcemia.
N Y State J Med. 1970 Jun 1;70(11):1298-9.
7
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8
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J Immunol Methods. 1972 Nov;2(1):99-114. doi: 10.1016/0022-1759(72)90022-1.
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Clin Immunol Immunopathol. 1973 Jan;1(2):220-9. doi: 10.1016/0090-1229(73)90022-6.
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