Maruyama Y
Department of Radiology, Shinshu University School of Medicine.
Nihon Igaku Hoshasen Gakkai Zasshi. 1998 Aug;58(9):509-15.
A high-quality, conventional chest radiograph should be obtained in lung cancer screening programs to efficiently detect the faint, small nodular shadows due to early lung cancer in the lung fields, although, it is difficult to image the entire lung field within the linear part of the characteristic curve of the screen/film system owing to the wide variation in tissue density in the thorax, which ranges from the well aerated lung superimposed on the intercostal spaces to the lung area superimposed on the heart or diaphragm. In the detection of early cancer in the lung fields, it is important to consider the very low density (CT values of nearly -600 HU to -300 HU) commonly exhibited by early adenocarcinomas in the lung. The detectability of such nodules would be greatly influenced by the contrast and noise characteristics of the photographic system, the complexity of anatomical structures around the nodule, the characteristics of the observation system for x-ray films, the interpreter, and so on. The choice of x-ray film/screen system basically determines the efficacy of screening; specifically, the contrast characteristics of x-ray films together with noise level, which varies at different optical densities, affect the detectability of nodular shadows. The present study was carried out to determine the most suitable sensitometric characteristics and to assess the effects of the noise level of the x-ray film/screen system on the detectability of nodular shadows within the lung fields, particularly in low-density areas.
在肺癌筛查项目中,应获取高质量的传统胸部X光片,以便有效地检测出肺野中因早期肺癌形成的 faint、小结节阴影,尽管由于胸部组织密度差异极大,从叠加在肋间间隙的通气良好的肺到叠加在心脏或膈肌上的肺区域,很难在屏/片系统特征曲线的线性部分内对整个肺野进行成像。在检测肺野中的早期癌症时,重要的是要考虑到肺内早期腺癌通常表现出的极低密度(CT值接近-600 HU至-300 HU)。此类结节的可检测性会受到摄影系统的对比度和噪声特性、结节周围解剖结构的复杂性、X光片观察系统的特性、解读人员等因素的极大影响。X光片/屏系统的选择基本上决定了筛查的效果;具体而言,X光片的对比度特性以及在不同光学密度下变化的噪声水平会影响结节阴影的可检测性。本研究旨在确定最合适的感光测定特性,并评估X光片/屏系统的噪声水平对肺野内结节阴影可检测性的影响,特别是在低密度区域。