Hickel R, Dasch W, Janda R, Tyas M, Anusavice K
Int Dent J. 1998 Feb;48(1):3-16. doi: 10.1111/j.1875-595x.1998.tb00688.x.
People worldwide have become increasingly aware of the potential adverse effects on the environment, of pollution control and of toxic effects of food, drugs and biomaterials. Amalgam and its potential toxic side effects (still scientifically unproven) continue to be discussed with increasing controversy by the media in some countries. Consequently, new direct restorative materials are now being explored by dentists, materials scientists and patients who are searching for the so-called 'amalgam substitute' or 'amalgam alternative'. From a critical point of view some of the new direct restorative materials are good with respect to aesthetics, but all material characteristics must be considered, such as mechanical properties, biological effects, and longterm clinical behaviour.
全世界的人们越来越意识到污染控制以及食品、药物和生物材料的毒性作用对环境的潜在不利影响。汞合金及其潜在的毒副作用（仍未得到科学证实）在一些国家仍不断被媒体以越来越大的争议进行讨论。因此，牙医、材料科学家以及正在寻找所谓“汞合金替代品”或“汞合金替代物”的患者，目前正在探索新型直接修复材料。从批判性的角度来看，一些新型直接修复材料在美学方面表现良好，但必须考虑所有材料特性，如机械性能、生物学效应和长期临床行为。
