Drexler W, Findl O, Menapace R, Rainer G, Vass C, Hitzenberger C K, Fercher A F
Institut für Medizinische Physik, Universität Wien, Vienna, Austria.
Am J Ophthalmol. 1998 Oct;126(4):524-34. doi: 10.1016/s0002-9394(98)00113-5.
To compare biometry performed by an enhanced version of dual beam partial coherence interferometry and applanation ultrasound in a prospective study of 85 cataract eyes to improve refractive outcome of cataract surgery due to a more accurate calculation of intraocular lens power.
The SRK II formula using ultrasound biometry data was employed. Three months after surgery, partial coherence interferometry biometry was repeated and refractive outcome was determined. Preoperative partial coherence interferometry biometry data were used to determine the refractive power of the intraocular lenses retrospectively and to calculate the possible refractive outcome.
Precision of partial coherence interferometry biometry was more than 10 times better than that of ultrasound. Therefore, the possible mean absolute error for postoperative refraction achieved with partial coherence interferometry biometry was 0.49 diopters (compared with 0.67 diopters with ultrasound biometry), resulting in an improvement of 27%. Axial eye length measured with the two techniques differed by a mean of 460 microm. The difference in lens thickness measured with partial coherence interferometry and ultrasound significantly correlated with cataract grade. A mean shortening of 120 microm of axial eye length following cataract surgery was also detected by partial coherence interferometry.
The enhanced version of partial coherence interferometry offers biometry with unprecedented precision (<10 microm) and resolution (approximately 12 microm), therefore improving the refractive outcome in cataract surgery. This noninvasive technique provides a high degree of comfort for the patient, with no need for local anesthesia or pupil dilation and minimized risk of corneal infection.
在一项对85只白内障眼的前瞻性研究中，比较增强版双光束部分相干干涉测量法与压平式超声生物测量法，以通过更精确地计算人工晶状体度数来改善白内障手术的屈光效果。
采用基于超声生物测量数据的SRK II公式。术后三个月，重复进行部分相干干涉测量法生物测量并确定屈光效果。术前部分相干干涉测量法生物测量数据用于回顾性确定人工晶状体的屈光力并计算可能的屈光效果。
部分相干干涉测量法生物测量的精度比超声测量法高10倍以上。因此，部分相干干涉测量法生物测量术后屈光的可能平均绝对误差为0.49屈光度（超声生物测量法为0.67屈光度），提高了27%。两种技术测量的眼轴长度平均相差460微米。部分相干干涉测量法和超声测量的晶状体厚度差异与白内障分级显著相关。部分相干干涉测量法还检测到白内障手术后眼轴长度平均缩短120微米。
增强版部分相干干涉测量法提供了前所未有的精度（<10微米）和分辨率（约12微米）的生物测量，从而改善了白内障手术的屈光效果。这种非侵入性技术为患者提供了高度的舒适度，无需局部麻醉或瞳孔散大，且角膜感染风险降至最低。
