Findl O, Drexler W, Menapace R, Hitzenberger C K, Fercher A F
Universitätsklinik für Augenheilkunde, Allgemeines Krankenhaus Wien, Vienna, Austria.
J Cataract Refract Surg. 1998 Aug;24(8):1087-93. doi: 10.1016/s0886-3350(98)80102-8.
To investigate the applicability of the scanning version of dual-beam partial coherence interferometry (PCI) for measuring the anterior segment and axial length of pseudophakic eyes in a clinical setting and to determine the achievable precision with this biometry technique.
Department of Ophthalmology, Vienna General Hospital, and Institute of Medical Physics, University of Vienna, Austria.
Partial coherence interferometry was performed in 39 pseudophakic eyes of 39 patients after implantation of a foldable acrylic intraocular lens (IOL).
Effective lens position (ELP), IOL thickness and lens-capsule distance (LCD) were determined with a precision of 2 to 3 microns; corneal thickness and axial eye length, with a precision of 0.8 and 5.0 microns, respectively. The mean ELP of the IOL was 4.093 mm +/- 0.290 (SD). In 7 eyes (18%), a positive LCD of 68 +/- 40 microns was detected with PCI. Mean corneal thickness was 526.4 +/- 31.5 microns; mean IOL thickness, 791.5 +/- 40.2 microns; and mean axial length, 23.388 +/- 0.824 mm.
The scanning version of PCI enables high precision (< or = 5 microns) and high resolution (approximately 12 microns) biometry of pseudophakic eyes that is better than conventional ultrasound by a factor of more than 20. For the first time, positive LCD, a possible risk factor for posterior capsule opacification, could be detected and quantified. Furthermore, this technique offers a high degree of comfort for the patient since it is a noncontact method with no need for local anesthesia or pupil dilation and has a reduced risk of corneal infection.
研究双光束部分相干干涉测量术（PCI）扫描版在临床环境中测量人工晶状体眼眼前节和眼轴长度的适用性，并确定该生物测量技术可达到的精度。
奥地利维也纳总医院眼科以及维也纳大学医学物理研究所。
对39例植入可折叠丙烯酸人工晶状体（IOL）后的患者的39只人工晶状体眼进行部分相干干涉测量。
有效晶状体位置（ELP）、人工晶状体厚度和晶状体 - 囊膜距离（LCD）的测量精度为2至3微米；角膜厚度和眼轴长度的测量精度分别为0.8微米和5.0微米。人工晶状体的平均ELP为4.093毫米±0.290（标准差）。通过PCI在7只眼（18%）中检测到正的LCD为68±40微米。平均角膜厚度为526.4±31.5微米；平均人工晶状体厚度为791.5±40.2微米；平均眼轴长度为23.388±0.824毫米。
PCI扫描版能够对人工晶状体眼进行高精度（≤5微米）和高分辨率（约12微米）的生物测量，比传统超声精确20倍以上。首次能够检测并量化正的LCD，这是后囊膜混浊的一个可能危险因素。此外，该技术为患者提供了高度的舒适度，因为它是非接触式方法，无需局部麻醉或散瞳，且角膜感染风险降低。
