Suppr超能文献

1993年至2012年澳大利亚新南威尔士州老年人侵袭性脑膜炎球菌病

Invasive meningococcal disease in elderly people, New South Wales, Australia, 1993 to 2012.

作者信息

Gunaratnam Praveena, Massey Peter, Durrheim David, Torvaldsen Siranda

机构信息

New South Wales Public Health Officer Training Program, New South Wales Health, Sydney, Australia . ; School of Public Health and Community Medicine, University of New South Wales, Sydney, Australia .

Hunter New England Population Health, Newcastle, Australia . ; School of Nursing, Midwifery & Nutrition, James Cook University, Townsville, Australia .

出版信息

Western Pac Surveill Response J. 2013 Dec 9;4(4):4-10. doi: 10.5365/WPSAR.2013.4.4.001. eCollection 2013 Oct-Dec.

Abstract

Little information is available publicly on invasive meningococcal disease (IMD) in elderly people in Australia. This study analysed IMD notifications data from New South Wales between 1993 and 2012 to determine the distribution of IMD among people aged 65 years and older and to describe the characteristics of IMD in this age group compared to younger age groups with respect to notification trends, serogroup distribution and mortality rates. Following introduction of a childhood vaccination programme against meningococcal type C in 2003, notification rates in all age groups decreased, but the proportion of IMD notifications in people aged 65 years and over rose significantly (from 4% to 6%, P = 0.01). Mortality rates from IMD in those aged 65 years and older were significantly higher than overall rates (32% compared to 5%, P < 0.01). Serogroup Y accounted for 23% of infections in the elderly compared to 3% in people aged under 65 years (P < 0.01). As the population ages, the elderly may account for a higher number of IMD cases in Australia. Protocols at the state and national level should be updated to provide guidance on the clinical and public health management of elderly people with IMD.

摘要

关于澳大利亚老年人侵袭性脑膜炎球菌病(IMD)的公开信息很少。本研究分析了1993年至2012年新南威尔士州的IMD通报数据,以确定65岁及以上人群中IMD的分布情况,并描述该年龄组与较年轻年龄组相比在通报趋势、血清群分布和死亡率方面的IMD特征。2003年引入针对C型脑膜炎球菌的儿童疫苗接种计划后,所有年龄组的通报率均下降,但65岁及以上人群中IMD通报的比例显著上升(从4%升至6%,P = 0.01)。65岁及以上人群中IMD的死亡率显著高于总体死亡率(分别为32%和5%,P < 0.01)。Y血清群在老年人感染中占23%,而在65岁以下人群中占3%(P < 0.01)。随着人口老龄化,澳大利亚老年人中IMD病例数可能会增加。应更新州和国家层面的方案,为患有IMD的老年人的临床和公共卫生管理提供指导。

相似文献

引用本文的文献

9
New South Wales annual vaccine-preventable disease report, 2013.《2013年新南威尔士州年度疫苗可预防疾病报告》
Western Pac Surveill Response J. 2015 Apr 22;6(2):37-44. doi: 10.5365/WPSAR.2014.5.4.009. eCollection 2015 Apr-Jun.

本文引用的文献

4
The changing and dynamic epidemiology of meningococcal disease.脑膜炎奈瑟菌病的变化和动态流行病学。
Vaccine. 2012 May 30;30 Suppl 2:B26-36. doi: 10.1016/j.vaccine.2011.12.032. Epub 2011 Dec 15.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验