Dipierri J E, Alfaro E, Bejarano I F, Etchart A A
Instituto de Biología de la Altura, Universidad Nacional de Jujuy, San Salvador de Jujuy, Argentina.
Hum Biol. 1998 Oct;70(5):959-64.
We determined acetylator phenotypes by means of a sulfadimidine test and found that 39% of the native population of the province of Jujuy, in northwestern Argentina, have slow acetylators. The frequency of the allele controlling slow acetylation was estimated at q = 0.65 +/- 0.001. This estimate differs from those previously recorded in native and Mestizo American populations. A review of the literature on acetylator phenotypes in the Americas revealed that it is not possible to discern any clear pattern of distribution in relation to the geographic variability observed.
我们通过磺胺二甲嘧啶试验确定了乙酰化表型，发现阿根廷西北部胡胡伊省的本地人群中有39%为慢乙酰化者。控制慢乙酰化的等位基因频率估计为q = 0.65±0.001。这一估计值与之前在美洲本地人和混血人群中记录的不同。对美洲乙酰化表型文献的综述表明，无法辨别出与所观察到的地理变异性相关的任何清晰分布模式。
