对法国国王路易十六和玛丽·安托瓦内特一位假定儿子遗骸的线粒体DNA分析。
Mitochondrial DNA analysis on remains of a putative son of Louis XVI, King of France and Marie-Antoinette.
作者信息
Jehaes E, Decorte R, Peneau A, Petrie J H, Boiry P A, Gilissen A, Moisan J P, Van den Berghe H, Pascal O, Cassiman J J
机构信息
Center for Human Genetics, University of Leuven, Belgium.
出版信息
Eur J Hum Genet. 1998 Jul-Aug;6(4):383-95. doi: 10.1038/sj.ejhg.5200227.
Carl Wilhelm Naundorff was buried in 1845 in Delft as Louis Charles, Duc de Normandie, 'Louis XVII'. However, the son of Louis XVI and Marie-Antoinette-Louis XVII--officially died in the Temple of Paris in 1795. In order to resolve the identity of Naundorff, mitochondrial DNA (mtDNA) D-loop sequences of his remains were compared with the sequences obtained from the hairs of two sisters of Marie-Antoinette, Marie-Antoinette herself, and with the sequences obtained from DNA samples of two living maternal relatives. The mtDNA sequence of a bone sample from Naundorff showed two nucleotide differences from the sequences of the three sisters and four differences from the sequences of living maternal relatives. Based on this evidence it becomes very unlikely that Naundroff is the son of Marie-Antoinette.
卡尔·威廉·瑙多夫于1845年被葬于代尔夫特，身份是路易·夏尔，诺曼底公爵，“路易十七”。然而，路易十六和玛丽·安托瓦内特的儿子——路易十七——官方记录是于1795年死于巴黎圣殿。为了确定瑙多夫的身份，将其遗体的线粒体DNA（mtDNA）D环序列与从玛丽·安托瓦内特的两位姐妹、玛丽·安托瓦内特本人的头发中获得的序列，以及从两位在世母系亲属的DNA样本中获得的序列进行了比较。来自瑙多夫的一块骨头样本的mtDNA序列与三位姐妹的序列有两个核苷酸差异，与在世母系亲属的序列有四个差异。基于这一证据，瑙多夫极不可能是玛丽·安托瓦内特的儿子。
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