Bridgen A, Kocherhans R, Tobler K, Carvajal A, Ackermann M
Institute of Virology, University of Zurich, Switzerland.
Adv Exp Med Biol. 1998;440:781-6. doi: 10.1007/978-1-4615-5331-1_101.
We report here the continued determination and analysis of the nucleotide sequence of both wild type (wt) and cell culture adapted (ca) porcine epidemic diarrhoea coronavirus (PEDV). These studies were undertaken with two objectives in mind: the identification of common and divergent features in the genomic sequences of wt and ca PEDV which can explain the differences in virulence of these isolates and the further exploration of the relationship of PEDV to other coronaviruses.
我们在此报告对野生型（wt）和细胞培养适应型（ca）猪流行性腹泻冠状病毒（PEDV）核苷酸序列的持续测定和分析。开展这些研究有两个目的：一是鉴定野生型和细胞培养适应型PEDV基因组序列中的共同特征和差异特征，以解释这些分离株毒力的差异；二是进一步探究PEDV与其他冠状病毒之间的关系。
