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[患有和未患有慢性腹痛的儿童血清幽门螺杆菌IgG抗体升高的发生率]

[Incidence of increased serum Helicobacter pylori IgG antibodies in children with and without chronic abdominal pain].

作者信息

Blümel P, David M, Hirschl A M, König H

机构信息

G. v. Preyersches Kinderspital der Stadt Wien.

出版信息

Klin Padiatr. 1998 Sep-Oct;210(5):366-9. doi: 10.1055/s-2008-1043905.

DOI:10.1055/s-2008-1043905
PMID:9782482
Abstract

The prevalence of Helicobacter pylori (HP) IgG antibodies was analysed in a group of 142 asymptomatic children (group A) and in 31 pediatric patients (group B) with recurrent abdominal pain. HP IgG antibodies were measured by a commercially available fluorescence-enzyme immuno-assay test (Heloritest IgG, Fa Eurospital). In asymptomatic children the prevalence of HP IgG antibodies increased significantly with age from 17% with 6 years to more then 40% with 14 years. A higher prevalence of HP IgG antibodies was found in children living in more crowded housing conditions. Comparing the number of HP IgG positive children in group B (58%) to a matched population from group A (35%) no statistically different prevalence rates were found. Thus HP IgG antibodies are found in similar frequencies, in both, symptomatic and asymptomatic children. Therefore the presence of HP-IgG antibodies does not necessarily indicate that the HP infection is the cause for the recurrent abdominal pain in these children.

摘要

对142名无症状儿童(A组)和31名患有复发性腹痛的儿科患者(B组)进行了幽门螺杆菌(HP)IgG抗体患病率分析。采用市售荧光酶免疫测定试验(Heloritest IgG,Fa Eurospital)检测HP IgG抗体。在无症状儿童中,HP IgG抗体患病率随年龄显著增加,6岁时为17%,14岁时超过40%。居住在住房条件更拥挤环境中的儿童HP IgG抗体患病率更高。将B组中HP IgG阳性儿童的数量(58%)与A组匹配人群(35%)进行比较,未发现患病率有统计学差异。因此,有症状和无症状儿童中HP IgG抗体的出现频率相似。所以,HP-IgG抗体的存在不一定表明HP感染是这些儿童复发性腹痛的原因。

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