Conrozier T, Jousseaume C A, Mathieu P, Tron A M, Caton J, Bejui J, Vignon E
Service de rhumatologie, Centre hospitalier Lyon-Sud, Pierre-Bénite, France.
Br J Rheumatol. 1998 Sep;37(9):961-8. doi: 10.1093/rheumatology/37.9.961.
To evaluate the rate of progression of radiological joint space narrowing (JSN) in patients operated on for hip osteoarthritis (OA) and to determine its predictive factors.
retrospective longitudinal trial of 61 patients who underwent total hip arthroplasty (THA) for hip OA (69 operated hips). Mean follow-up 81.2 +/- 9.9 months. Collected data: (1) standing frontal radiographs of the pelvis from diagnosis to surgery (246 films) for morphological evaluation and quantitative measurement of joint space width (JSW) (computerized reading of digitized X-rays); (2) demographic data (sex, age, body mass index, smoking status, professional and sporting activities, family history of OA); (3) clinical data (age at onset-diagnosis and THA, drug consumption, time from diagnosis to permanent disability, OA at other joints, previous THA of the contralateral hip).
multivariate analysis.
The yearly mean narrowing (YMN) of MeanJSW was 0.43 +/- 0.43 mm/yr (median 0.29, range 0.03-2.55). YMN correlated inversely with joint space width at operation and follow-up duration, and was increased in atrophic OA (r = 0.71). The time between diagnosis and THA correlated with JSW at diagnosis, and was inversely correlated with age at onset and YMN. It was longer in patients with hypertrophic OA (r = 0.69).
Rapid progression of JSN, older age and absence of osteophytes appear to be the main factors leading to THA.
评估接受髋关节骨关节炎(OA)手术患者的放射学关节间隙狭窄(JSN)进展率,并确定其预测因素。
对61例行全髋关节置换术(THA)治疗髋关节OA的患者(69个手术髋关节)进行回顾性纵向试验。平均随访81.2±9.9个月。收集的数据:(1)从诊断到手术的骨盆站立位正位X线片(246张),用于形态学评估和关节间隙宽度(JSW)的定量测量(数字化X线的计算机化读取);(2)人口统计学数据(性别、年龄、体重指数、吸烟状况、职业和体育活动、OA家族史);(3)临床数据(发病诊断和THA时的年龄、药物消耗、从诊断到永久性残疾的时间、其他关节的OA、对侧髋关节先前的THA)。
多变量分析。
平均JSW的年平均狭窄(YMN)为0.43±0.43mm/年(中位数0.29,范围0.03 - 2.55)。YMN与手术时及随访期间的关节间隙宽度呈负相关,在萎缩性OA中增加(r = 0.71)。诊断与THA之间的时间与诊断时的JSW相关,与发病年龄和YMN呈负相关。在肥厚性OA患者中时间更长(r = 0.69)。
JSN的快速进展、年龄较大和无骨赘似乎是导致THA的主要因素。