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蜡样芽孢杆菌将白藜芦醇转化为白藜芦醇糖苷。

Biotransformation of resveratrol to piceid by Bacillus cereus.

作者信息

Cichewicz R H, Kouzi S A

机构信息

Division of Basic Pharmaceutical Sciences, School of Pharmacy, Northeast Louisiana University, Monroe, Louisiana 71209, USA.

出版信息

J Nat Prod. 1998 Oct;61(10):1313-4. doi: 10.1021/np980139b.

Abstract

Microbial transformation of resveratrol (1), trans-3,4', 5-trihydroxystilbene, was studied. Preparative scale biotransformation of 1 with whole-cell suspensions of Bacillus cereus UI 1477 resulted in the production of metabolite 2 which was identical in all respects to an authentic sample of piceid, resveratrol 3-O-beta-D-glucoside.

摘要

研究了白藜芦醇(1),反式-3,4',5-三羟基芪的微生物转化。用蜡样芽孢杆菌UI 1477的全细胞悬浮液对1进行制备规模的生物转化,产生了代谢物2,其在各方面均与白藜芦醇3-O-β-D-葡萄糖苷(云杉新苷)的正品样品相同。

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