采用超出美国疾病控制与预防中心（CDC）指南的青霉素方案治疗母体梅毒后发生的先天性梅毒
Congenital syphilis after treatment of maternal syphilis with a penicillin regimen exceeding CDC guidelines.
作者信息
Conover C S, Rend C A, Miller G B, Schmid G P
机构信息
Illinois Department of Public Health, Division of Infectious Diseases, Chicago, USA.
出版信息
Infect Dis Obstet Gynecol. 1998;6(3):134-7. doi: 10.1002/(SICI)1098-0997(1998)6:3<134::AID-IDOG7>3.0.CO;2-X.
BACKGROUND
Although congenital syphilis usually occurs as a result of a failure to detect and treat syphilis in pregnant women, failures of the currently recommended regimen to prevent congenital syphilis have been reported.
CASE
This report describes an infant with congenital syphilis despite maternal treatment with a regimen exceeding current CDC guidelines.
CONCLUSION
Regardless of the regimen used to treat syphilis during pregnancy, clinicians should recognize the possibility of occasional treatment failures and the importance of adequate follow-up of infants at risk for congenital syphilis.
背景
虽然先天性梅毒通常是由于未能检测和治疗孕妇梅毒所致，但已有报告称目前推荐的预防先天性梅毒的方案存在失败情况。
病例
本报告描述了一名先天性梅毒婴儿，其母亲接受的治疗方案超出了当前美国疾病控制与预防中心的指南。
结论
无论孕期治疗梅毒采用何种方案，临床医生都应认识到偶尔出现治疗失败的可能性，以及对有先天性梅毒风险的婴儿进行充分随访的重要性。
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