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复制腺病毒5型DNA时单链DNA的性质。

Nature of the single-stranded DNA in replicating adenovirus type 5 DNA.

作者信息

Sussenbach J S, Tolun A, Pettersson U

出版信息

J Virol. 1976 Nov;20(2):532-4. doi: 10.1128/JVI.20.2.532-534.1976.

Abstract

Single-stranded regions in replicating adenovirus type 5 DNA were isolated and hybridized in solution to the separated strands of adenovirus 2 or 5 DNA. The results showed that the two strands of adenovirus 5 DNA are exposed to almost the same extent during replication, suggesting that displacement synthesis may start from either end of the viral DNA.

摘要

分离出正在复制的5型腺病毒DNA中的单链区域,并使其在溶液中与2型或5型腺病毒DNA的分离链杂交。结果表明,5型腺病毒DNA的两条链在复制过程中暴露程度几乎相同,这表明置换合成可能从病毒DNA的任一端开始。

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