Guerin F, Perrier-Gros-Claude J D, Foissaud V, Masseron T, Thierry J
Service de Biologie médicale, Hôpital d'instruction des Armées Desgenettes, Lyon.
Presse Med. 1998 Sep 26;27(28):1427-9.
Assess the prevalence of asymptomatic carriage of vancomycin-resistant Enterococci in a population of healthy young French subjects.
Stool samples obtained from 100 persons living in south-eastern France (20 sampling sites) were directly seeded on enriched selective media containing 6 mg/l vancomycin. Bacterial species and their resistant gene were identified with classical methods and multiplex genomic amplification.
The incidence of asymptomatic carriage was 17% with a homogeneous geographic distribution of the resistant strains. Nine Enterococcus faecium van A strains and 8 E. gallinarum van C1 strains were isolated.
These findings demonstrate carriage of vancomycin-resistant Enterococci in a population of young ambulatory subjects in France. The incidence observed was much higher than in an earlier study conducted in France. These results might be explained by a much more sensitive detection technique. Care should be taken to avoid dissemination in hospital settings.
评估健康法国年轻人群中耐万古霉素肠球菌的无症状携带率。
从法国东南部100名居住者（20个采样点）获取粪便样本，直接接种于含6 mg/l万古霉素的富集选择性培养基上。采用经典方法和多重基因组扩增鉴定细菌种类及其耐药基因。
无症状携带率为17%，耐药菌株在地理分布上较为均匀。分离出9株粪肠球菌van A菌株和8株鹑鸡肠球菌van C1菌株。
这些发现表明法国年轻非卧床人群中存在耐万古霉素肠球菌携带情况。观察到的发病率远高于法国早期开展的一项研究。这些结果可能是由于检测技术更为灵敏。应注意避免在医院环境中传播。
