Kern W H, Stiles Q R
J Thorac Cardiovasc Surg. 1976 Nov;72(5):801-8.
Two cases of pulmonary blastoma are reported. One occurred in a 29-year-old man 31 months after a cyst had been excised from the same pericardial-pleural area. The cyst appeared to be of mesothelial origin and, although supported by a cellular stroma, was originally considered to be benign. The morphologic features, location, and possible relationship to a mesothelial lesion suggest an embryonal-mesothelial origin of the tumor. The patient died of recurrent and metastatic disease 9 years after the first resection. The second case is that of a now 74-year-old woman who, over a period of 19 years, has had six separate small peripheral lung tumors excised. They originally resembled fibrous hamartomas but included embryonal-type immature areas and became increasingly more cellular and sarcomatous. The fine structure of the recurrent tumors is that of primitive stroma with few fibrils but no other differentiating features.
报告了两例肺母细胞瘤。其中一例发生在一名29岁男性身上，在同一心包 - 胸膜区域的囊肿切除31个月后发病。该囊肿似乎起源于间皮，尽管有细胞性间质支持，但最初被认为是良性的。肿瘤的形态特征、位置以及与间皮病变的可能关系提示其起源于胚胎性间皮。该患者在首次切除9年后死于复发和转移性疾病。第二例是一名74岁女性，在19年的时间里，先后有6个位于肺外周的小肿瘤被切除。这些肿瘤最初类似纤维性错构瘤，但包含胚胎型未成熟区域，且细胞成分越来越多，呈肉瘤样。复发肿瘤的精细结构为原始间质，纤维很少，但无其他分化特征。
