Burke W J, Roccaforte W H, Wengel S P, McArthur-Miller D, Folks D G, Potter J F
Department of Psychiatry, University of Nebraska College of Medicine, Omaha, USA.
Am J Geriatr Psychiatry. 1998 Fall;6(4):308-19.
The authors investigated sources of disagreement on the Geriatric Depression Scale (GDS) between patients and their collateral sources (CSs). There were 198 subjects with possible or probable Alzheimer's disease (DAT) and 64 cognitively intact subjects evaluated at an outpatient geriatric assessment center. The 30-item GDS was completed by the patient and the CS version of the GDS by the CS. A sizable discrepancy was found in the reporting of depressive symptoms by the subjects vs. the CSs. Multiple-regression analyses revealed that both level of insight and level of physical illness in the subjects with DAT significantly influenced the discrepancy. An increased sense of burden in the CSs was associated with a larger symptom gap in both DAT and control subjects. CSs consistently perceived more depressive symptoms than subjects, especially subjects with DAT who had no insight into their cognitive impairment.
作者调查了患者与其旁证来源（CSs）之间在老年抑郁量表（GDS）上的分歧来源。在一家门诊老年评估中心对198名可能或疑似患有阿尔茨海默病（DAT）的受试者以及64名认知功能正常的受试者进行了评估。患者完成30项GDS，旁证来源完成GDS的CS版本。结果发现，受试者与旁证来源在抑郁症状报告方面存在相当大的差异。多元回归分析显示，DAT受试者的洞察力水平和身体疾病水平均显著影响这种差异。旁证来源负担感的增加与DAT和对照组受试者中更大的症状差距相关。旁证来源始终比受试者察觉到更多的抑郁症状，尤其是那些对自己的认知障碍没有洞察力的DAT受试者。
