Tiwara S, Passey M, Clegg A, Mgone C, Lupiwa S, Suve N, Lupiwa T
Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea.
P N G Med J. 1996 Sep;39(3):234-8.
We conducted a community-based study of the prevalence of sexually transmitted diseases in rural and periurban communities in Eastern Highlands Province. We interviewed a stratified random sample of women and men, examined the women for evidence of sexually transmitted diseases (STDs) and collected specimens for diagnosis of syphilis, by serology and dark-field microscopy, gonorrhoea, by Gram stain and culture, chlamydial infection, by polymerase chain reaction (PCR) and direct immunofluorescence (DIF), trichomoniasis, by wet mount, and bacterial vaginosis, by wet mount and Gram stain. The men were tested for chlamydial infection only (first void urine tested by PCR and DIF). 201 women and 169 men were tested. Additionally, adults in the same communities who had not been randomly selected were offered the same services. An extra 243 women and 85 men were tested in this way. The laboratory results confirmed the clinical impression of an extremely high prevalence of STDs in this population. Among those randomly selected, 46% of the women had trichomonal vaginal infections and 26% had Chlamydia trachomatis infections detected by PCR, while 25% of the men had chlamydial infections. Other infections were much less common. 58% had one or more STDs. The prevalence of infection in self-selected adults was similar to that found in those randomly selected.
我们在东高地省的农村和城市周边社区开展了一项基于社区的性传播疾病患病率研究。我们对分层随机抽取的女性和男性进行了访谈，检查女性是否有性传播疾病（STD）的迹象，并采集标本用于梅毒诊断（通过血清学和暗视野显微镜检查）、淋病诊断（通过革兰氏染色和培养）、衣原体感染诊断（通过聚合酶链反应（PCR）和直接免疫荧光（DIF））、滴虫病诊断（通过湿片检查）以及细菌性阴道病诊断（通过湿片检查和革兰氏染色）。男性仅接受衣原体感染检测（通过PCR和DIF检测首次晨尿）。共对201名女性和169名男性进行了检测。此外，还为同一社区中未被随机选中的成年人提供了相同的服务。通过这种方式又对243名女性和85名男性进行了检测。实验室结果证实了该人群中性传播疾病患病率极高的临床印象。在随机抽取的人群中，46%的女性患有滴虫性阴道感染，26%的女性通过PCR检测出沙眼衣原体感染，而25%的男性患有衣原体感染。其他感染则较为少见。58%的人患有一种或多种性传播疾病。自行选择的成年人中的感染患病率与随机抽取的人群相似。
