van Winkelhoff A J, van Steenbergen T J, de Graaff J
Department of Oral Microbiology, Academic Center for Dentistry Amsterdam, The Netherlands.
J Endod. 1992 Sep;18(9):431-4. doi: 10.1016/s0099-2399(06)80843-5.
Porphyromonas endodontalis (formerly Bacteroides endodontalis) is a black-pigmented anaerobic Gram-negative rod which is associated with endodontal infections. It has been isolated from infected dental root canals and submucous abscesses of endodontal origin. The presence of P. endodontalis in infected dental root canals has been correlated with symptoms of an acute infection. It is occasionally found on oral mucous membranes and periodontal pockets. P. endodontalis has shown relatively low virulence in experimental monoinfections. In anaerobic mixed infections it can play an essential role. Differences in virulence between strains have been related to capsular material. On the basis of different types of capsules, three serotypes have been described. P. endodontalis is sensitive to a wide range of antibiotics, including the penicillins, the tetracyclines, and metronidazole.
牙髓卟啉单胞菌(以前称为牙髓拟杆菌)是一种产黑色色素的厌氧革兰氏阴性杆菌,与牙髓感染有关。它已从受感染的牙根管和牙髓源性粘膜下脓肿中分离出来。受感染牙根管中牙髓卟啉单胞菌的存在与急性感染症状相关。它偶尔出现在口腔粘膜和牙周袋中。牙髓卟啉单胞菌在实验性单一感染中显示出相对较低的毒力。在厌氧混合感染中它可发挥重要作用。菌株之间毒力的差异与荚膜物质有关。根据不同类型的荚膜,已描述了三种血清型。牙髓卟啉单胞菌对多种抗生素敏感,包括青霉素、四环素和甲硝唑。