Imir T, Gülmezoğlu E
Mikrobiyol Bul. 1976 Oct;10(4):437-48.
IgG and IgM were purified from human peripheral blood sera and IgA from human colostrum. A method is established to measure the Ig classes quantitatively which is a modification of Mancini's radialimmundiffusion technique. Three Ig clases were detected from 136 cancer patients and compared with 34 healthy controls. In sarcoma there was an increase in the 3 classes of Ig in serum. These differences were also significant in patients with bone tumors. A raised level of three classes of Ig was seen.