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1964年至1974年,皇家阿尔弗雷德王子医院的包虫病情况。

Hydatid disease at Royal Prince Alfred Hospital, 1964 to 1974.

作者信息

Little J M

出版信息

Med J Aust. 1976 Jun 12;1(24):903-8.

PMID:979745
Abstract

A survey of hydatid disease has been carried out at the Royal Prince Alfred Hospital over a ten-year period from 1964 to 1974. It would appear that there has been no change in incidence in hydatid disease in the last 25 years. Fifty per cent of the hydatid cysts dealt with in this series occurred in the liver, and 30% were in the lung. Forty per cent of patients with lung hydatid disease were found to harbour hydatid cysts in the liver as well, while 24% of those with hydatid disease in the liver were found to have co-existent lung cysts. Twenty per cent of patients with pulmonary hydatid cysts presented with urgent complications, while only 7% of those with liver hydatid cysts presented in this way. Twenty-four per cent of the patients in this series were born outside Australia, most of the rest having been born and having lived in New South Wales. In this State, the distribution of hydatid disease remains the same as it was in 1925. Of the serological tests, the Casoni intradermal reaction was positive in 67% of cases, while the complement-fixation reaction was positive in only 52%. Seventy-eight per cent of these patients came to operation; 50% were found to have viable cysts at operation. Morbidity was high from chest infection, prolonged drainage from the site of the cyst and subphrenic abscess. Since few viable cysts were found in patients over the age of 60 years, there is a strong case for conservatism in the treatment of elderly patient with an asymptomatic calcified hydatid cyst. The hydatid-dependent mortality rate in this series was 1-8%. Over a mean follow-up period of five years, in 5% of these patients, there was a proven recurrence of hydatid disease requiring further operation.

摘要

1964年至1974年的十年间,在皇家阿尔弗雷德王子医院开展了一项包虫病调查。过去25年里,包虫病的发病率似乎没有变化。该系列中处理的包虫囊肿有50%发生在肝脏,30%在肺部。发现40%的肺包虫病患者肝脏中也有包虫囊肿,而肝脏包虫病患者中有24%同时存在肺囊肿。20%的肺包虫囊肿患者出现紧急并发症,而肝脏包虫囊肿患者只有7%以这种方式就诊。该系列中24%的患者出生在澳大利亚境外,其余大多数人在新南威尔士州出生并生活。在该州,包虫病的分布与1925年相同。在血清学检测中,卡索尼皮内反应在67%的病例中呈阳性,而补体结合反应仅在52%的病例中呈阳性。这些患者中有78%接受了手术;50%在手术中发现有存活囊肿。胸部感染、囊肿部位长期引流和膈下脓肿导致的发病率很高。由于60岁以上患者中很少发现存活囊肿,对于无症状钙化包虫囊肿的老年患者,在治疗上有充分理由采取保守治疗。该系列中包虫病相关死亡率为1 - 8%。在平均五年的随访期内,这些患者中有5%被证实包虫病复发,需要进一步手术。

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