D'Ippoliti D, Davoli M, Perucci C A, Pasqualini F, Bargagli A M
Department of Epidemiology, Lazio Regional Health Authority, Rome, Italy.
Drug Alcohol Depend. 1998 Oct 1;52(2):167-71. doi: 10.1016/s0376-8716(98)00091-x.
Retention in treatment among 1503 heroin users attending public treatment centres in 1995 was studied. Three different treatments were considered: methadone maintenance, drug-free program and naltrexone. The retention rate after 1 year was 40% for patients in methadone maintenance, 18% in naltrexone and 15% in drug-free program. For patients in maintenance, methadone dosage and clinic policy were the most important factors for retention. Patients taking > or = 60 mg/day and 30-59 mg/day were respectively 70 and 50% more likely to remain in treatment than those receiving a < 30 mg daily dose. Patients in maintenance-oriented clinics were 30% more likely to remain in treatment than those in abstinence-oriented centres.
对1995年在公共治疗中心接受治疗的1503名海洛因使用者的治疗留存情况进行了研究。考虑了三种不同的治疗方法：美沙酮维持治疗、戒毒项目和纳曲酮。接受美沙酮维持治疗的患者1年后的留存率为40%，接受纳曲酮治疗的为18%，接受戒毒项目治疗的为15%。对于接受维持治疗的患者，美沙酮剂量和诊所政策是留存的最重要因素。每日服用≥60毫克和30 - 59毫克的患者继续接受治疗的可能性分别比每日剂量<30毫克的患者高70%和50%。以维持治疗为导向的诊所中的患者继续接受治疗的可能性比以戒毒为导向的中心中的患者高30%。
