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德国一家大学医院儿童及青少年血液使用情况调查

A survey of blood utilization in children and adolescents in a German university hospital.

作者信息

Zimmermann R, Handtrack D, Zingsem J, Weisbach V, Neidhardt B, Glaser A, Eckstein R

机构信息

Abteilung für Transfusionsmedizin und Hämostaseologie, Friedrich-Alexander-Universität, Erlangen-Nürnberg, Germany.

出版信息

Transfus Med. 1998 Sep;8(3):185-94. doi: 10.1046/j.1365-3148.1998.00159.x.

DOI:10.1046/j.1365-3148.1998.00159.x
PMID:9800290
Abstract

There are no detailed data on blood use with regard to diagnoses of recipients during infancy, childhood and adolescence. Available information on this issue is incomplete and no longer current. We conducted a survey of blood component use in children and adolescents in an acute-care university hospital in the greater area of Nuremberg between June 1994 and September 1996. Packed red blood cells (RBCs), fresh-frozen plasmas (FFPs) and platelet (PLT) components were evaluated for the recipients discharge diagnoses. Source study files were extracted from the hospital transfusion service and the medical records department. Transfused units were listed by broad diagnostic categories and leading diagnostic groups formed from principal diagnoses of the recipients according to the International Classification of Diseases, 9th edn (ICD-9). 34.3% of 2869 RBC cell units, 35.0% of 1095 FFP units and 5.0% of 1028 PLT components were used in patients with congenital diseases, mainly cardiac defects. The disease category neoplastic diseases was next most frequently associated with blood transfusion diagnosed in recipients of 23.9% of all RBCs, 15.6% of all FFP units and in 66.4% of all PLT units. Malignant diseases and benign haematological diseases (diagnostic categories II and IV) accounted for 68.9% of all costs of blood component transfusion. These findings demonstrate the increased importance of platelet transfusion for the organization of local and regional blood donation programmes and for cost analysis exercises. The study shows that detailed information on local blood use may be obtained quickly using available data collections of transfusion services and medical record departments.

摘要

关于婴儿期、儿童期和青少年期受血者诊断方面的用血详细数据并不存在。关于这个问题的现有信息不完整且已过时。我们于1994年6月至1996年9月期间,在纽伦堡大区的一家急症大学医院对儿童和青少年的血液成分使用情况进行了一项调查。对红细胞悬液(RBC)、新鲜冰冻血浆(FFP)和血小板(PLT)成分进行了受血者出院诊断评估。从医院输血服务部门和病历部门提取了源研究文件。根据国际疾病分类第9版(ICD - 9),按广泛诊断类别列出输血单位,并根据受血者的主要诊断形成主要诊断组。2869个红细胞单位中的34.3%、1095个新鲜冰冻血浆单位中的35.0%以及1028个血小板成分中的5.0%用于患有先天性疾病的患者,主要是心脏缺陷。肿瘤性疾病类别在受血者中其次最常与输血相关,在所有红细胞的23.9%、所有新鲜冰冻血浆单位的15.6%以及所有血小板单位的66.4%中被诊断出。恶性疾病和良性血液系统疾病(诊断类别II和IV)占所有血液成分输血费用的68.9%。这些发现表明血小板输血对于组织当地和区域献血计划以及成本分析活动的重要性日益增加。该研究表明,利用输血服务部门和病历部门现有的数据收集,可以快速获得关于当地用血的详细信息。

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