Malenka D J, O'Connor G T
Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.
Jt Comm J Qual Improv. 1998 Oct;24(10):594-600. doi: 10.1016/s1070-3241(16)30408-4.
The Northern New England Cardiovascular Disease Study Group, a voluntary regional consortium, includes all cardiothoracic surgeons and interventional cardiologists, as well as nurses, anesthesiologists, perfusionists, administrators, and scientists associated with the six medical centers in Maine, New Hampshire, and Vermont and one Massachusetts-based medical center that support coronary artery bypass graft (CABG) surgery and percutaneous coronary interventions (PCI). Since 1987 the group has met at least three times a year to foster improvements in patient care.
The group's activities have included continued monitoring of outcomes, training in continuous quality improvement, and a benchmarking effort that allowed institutions to learn from one another. In the postintervention period (mid-1991 through early 1992) there were 293 fewer deaths (n = 575) than the 868 expected. In 1995 a new cycle of quality improvement work aimed at identifying the causes and correlates of postoperative mortality began. Study groups for each institution were organized to examine issues related to death from low-output states.
Major improvement in hospital outcomes have occurred in relation to the improving technology (primarily coronary stenting). Near-twofold variability in the use of stents has led to vigorous discussions about the role of new devices.
Randomized clinical trials are very important to assessing the effects of specific treatments, but most of what is known about actual clinical care will come from observational studies. Demonstrating the variability in practice patterns can be a potent stimulus to try to answer the important questions.
新英格兰北部心血管疾病研究小组是一个自愿组成的地区性联盟,成员包括所有心胸外科医生和介入心脏病学家,以及与缅因州、新罕布什尔州和佛蒙特州的六个医疗中心以及一个位于马萨诸塞州的支持冠状动脉旁路移植术(CABG)和经皮冠状动脉介入治疗(PCI)的医疗中心相关的护士、麻醉师、灌注师、管理人员和科学家。自1987年以来,该小组每年至少会面三次,以促进患者护理的改善。
冠状动脉旁路移植术(CABG)手术研究进展:该小组的活动包括持续监测结果、持续质量改进培训以及一项基准评估工作,使各机构能够相互学习。在干预后期(1991年年中至1992年初),死亡人数比预期的868人少293人(n = 575)。1995年,一个旨在确定术后死亡率的原因及相关因素的质量改进工作新周期开始。为每个机构组织了研究小组,以研究与低心排血量状态导致的死亡相关的问题。
经皮冠状动脉介入治疗(PCI)研究进展:随着技术(主要是冠状动脉支架置入术)的改进,医院治疗结果有了重大改善。支架使用方面近两倍的差异引发了关于新设备作用的激烈讨论。
随机临床试验对于评估特定治疗的效果非常重要,但关于实际临床护理的大部分知识将来自观察性研究。证明实践模式的差异可能是试图回答重要问题的有力刺激因素。