White D, Royston B
Department of Anaesthesia, Northwick Park Hospital, Harrow, UK.
Anaesthesia. 1998 Jun;53(6):555-9. doi: 10.1046/j.1365-2044.1998.00367.x.
We studied a group of spontaneously breathing patients anaesthetised for routine orthopaedic surgery using a circle system and isoflurane in a Komesaroff vaporiser within the circle. We observed and recorded: (1) the change in inspired isoflurane concentration caused by changing the fresh gas flow, (2) the increased respiration produced by surgical stimulus and the resulting increase in isoflurane concentration, (3) the respiratory depression produced by opioids and the consequent decrease in isoflurane concentration. We consider this regulation of anaesthetic uptake by the patient to be beneficial.
我们研究了一组接受常规骨科手术麻醉的自主呼吸患者，使用循环系统和异氟烷，异氟烷通过循环系统中的科梅萨罗夫蒸发器输送。我们观察并记录了：(1) 新鲜气体流量变化引起的吸入异氟烷浓度变化；(2) 手术刺激导致的呼吸增强以及由此引起的异氟烷浓度增加；(3) 阿片类药物引起的呼吸抑制以及随之而来的异氟烷浓度降低。我们认为患者对麻醉药摄取的这种调节是有益的。
