Antoine J C, Prina E, Lang T, Courret N
Dépt de Physiopathologie, Institut Pasteur, Paris, France.
Trends Microbiol. 1998 Oct;6(10):392-401. doi: 10.1016/s0966-842x(98)01324-9.
Leishmania are protozoan parasites that, as amastigotes, live in the macrophages of mammalian hosts within compartments called parasitophorous vacuoles. These organelles share features with late endosomes/lysosomes and are also involved in the trafficking of several major histocompatibility complex (MHC)-encoded molecules. Improved knowledge of the parasitophorous vacuoles may help clarify how these protozoa persist in their hosts.
利什曼原虫是原生动物寄生虫，作为无鞭毛体，生活在哺乳动物宿主巨噬细胞内称为寄生泡的区室中。这些细胞器与晚期内体/溶酶体具有共同特征，并且还参与几种主要组织相容性复合体（MHC）编码分子的运输。对寄生泡的深入了解可能有助于阐明这些原生动物如何在其宿主中持续存在。
