Vodolazhskaya M G
Department of Physiology, State University, Stavropol.
Neurosci Behav Physiol. 1998 Sep-Oct;28(5):527-32. doi: 10.1007/BF02463013.
Experiments were carried out on rats to study the dynamics of recovery of a conditioned reflex to time after electrolytic lesioning of the dorsal hippocampus and the effects of hippocampectomy on the development of this response. Lesioning of the hippocampus deranged the restoration of a conditioned reflex to time which had been fixed before surgery. In conditions of limited hippocampal damage, the conditioned reflex to time recovered earlier than in sham-operated animals. Animals with more significant damage showed delays in the recovery of the response to time. After hippocampectomy without initial training, the conditioned reflex to time could not be developed regardless of the extent of damage to the hippocampus. This process was also not affected by doses of phenamine of 0.05 mg/kg.
在大鼠身上进行了实验，以研究背侧海马体电解损伤后条件反射对时间恢复的动态变化，以及海马切除术对这种反应发展的影响。海马体损伤扰乱了术前已建立的对时间的条件反射的恢复。在海马体损伤有限的情况下，对时间的条件反射比假手术动物恢复得更早。损伤更严重的动物对时间的反应恢复延迟。在没有初始训练的情况下进行海马切除术后，无论海马体损伤程度如何，都无法建立对时间的条件反射。这个过程也不受0.05mg/kg苯丙胺剂量的影响。
